Encapsulated butylated hydroxyanisole (BHA) interaction with phospholipid liposomes as monitored by confocal Raman spectroscopy

International Conference on Food Chemistry & Hydrocolloids

August 11-12, 2016 Toronto, Canada

Afef Janen

Alabama A & M University, USA

Posters & Accepted Abstracts: J Exp Food Chem

Abstract :

Liposome carriers may be used for delayed release of butylated hydroxyanisole (BHA), a lipophilic-hydrophobic antioxidant. The purpose of this research was to investigate molecular interactions between the BHA and the liposomal structure by using Raman spectroscopy. Using a modified dehydration-rehydration method, BHA was dissolved in methanol and incorporated into the liposomes. Confocal Raman analysis of interactions was characterized on the different regions of the liposome phospholipid. The spectra of the BHA alone compared to the BHA in methanol were similar. Raman spectra of liposomes with and without BHA were recorded where the C-N stretching region in the head group shows a major band at 714 cm-1 and a vibration at 695 cm 1, a characteristic of BHA ring. Raman spectroscopy enabled us to generate spectra of the different components of the lipid bilayer and the antioxidant BHA. The findings showed that there was a difference between Raman spectra of lipid capsules and lipid capsules containing BHA. These results demonstrated that there was an interaction between the antioxidant BHA and liposomal vesicles.

Biography :

Email: afef.janen@gmail.com