Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

Open Access

Current Issue

Volume 7, Issue 1 (2021)

    Commentary Pages: 1 - 2

    Substitute Inebriant for Pharmaceutical Analysis

    John Andreus

    The analytical methods of greening have gained rising interest in the field of pharmaceuticals to improve the health safety of analysts and to decrease environmental impacts. Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most widely used analytical technique in pharmaceutical drug development and manufacturing such as the quality control of bulk drugs and pharmaceutical formulations, along with the analysis of drugs in biological samples. However, RP-HPLC methods commonly use large amounts of organic solvents and generate high quantities of waste to be disposed of, leading to some issues in terms of ecological impact and operator safety. In these contents, greening HPLC methods is becoming highly desirable. One strategy to reduce the impact of hazardous solvents is to replace classically used organic solvents with greener ones. As yet, ethanol has been the most often used alternative organic solvent.

    Commentary Pages: 1 - 2

    Medicinal Plants as Therapeutic Options for Topical Treatment in Canine Dermatology

    Nourdine Cheikh

    Medical plants have been utilized customarily since hundreds of years for wound consideration and treatment of skin illnesses both in human and creatures. Skin sicknesses are perhaps the most well-known purposes behind proprietors to take their canine to the veterinarian. The requests for treatment and prophylaxis of these sicknesses are wide. A wide scope of microscopic organisms including anti-toxin safe microorganisms can be included, making the treatment testing and bear an anthropo-zoonotic potential. The point of this survey is to methodicallly assess dependent on late logical writing, the capability of four restorative plants to advance the helpful alternatives in pyoderma, canine atopic dermatitis, otitis externa, wounds and dermatophytosis in canines.
                     Skin infections are perhaps the most widely recognized explanations behind proprietors to take their canine to the veterinarian. Canine skin illnesses incorporate bacterial skin contaminations, excessive touchiness problems, canine atopic dermatitis (CAD), food antagonistic responses, otitis externa, wounds, dermatophytosis, neoplasia and parasitic pervasions ; a scope of infections with different etiologies and manifestations and hence assorted requests for treatment.

    Short Communication Pages: 1 - 2

    An Ethnobotanical Survey of Medicinal Plants Used in the East Sepik Province of Papua New Guinea

    Kutan Ahorangi

    Therapeutic plant use between four unmistakable lingo study regions in the ES Province of PNG indicated that solitary a little part of plants had shared use in every territory, anyway generally using distinctive plant parts, being readied diversely and to treat distinctive ailments. A few occurrences of already unreported therapeutic plants could be found. Therapeutically under-and over-used plants were discovered both in the provincial reports and in a transregional examination, in this way demonstrating that these restorative usage frequencies contrast between regions. As a rule, when various names for similar species were discovered, we endeavored to coordinate plant family names to the PNG Plant Database variants to consider quantitative examination. Plant families which are considered abused have a substandard tenable stretch that lies over the predominant trustworthy span for the local complete information. Plant families that are considerend underused have a prevalent sound stretch underneath the second rate believable time period provincial complete informational collection dispersion. In any case, among the plants distinguished to species level, just four species were accounted for in each overview: Alstonia scholaris (L.) R.Br, Cassia alata L, Passiflora foetida L, and Zingiber officianale Roscoe. This unmistakably infers an otherworldly/enchanted association of plant and patient. Conventional review of the data assembled yielded data about plants not broadly utilized, inadequately clarified or utilized for unexpected infirmities in comparison to those in districts where utilization of the plant is more normal.

    Short Communication Pages: 1 - 2

    Tragia Species Ability for a Pharmacological Purpose

    Madeline Evens

    In the new situation of arising illnesses and worldwide pandemic, botanicals are acquiring enormous prominence. Plants fill in as source components and supplements for boosting resistance just as medication atoms. A portion of these plants is appealing as a result of their shading, fragrance, propensity, or natural job. A couple of plants are stinging too. Stinging plants are stinging, a versatile methodology developed in plants against herbivores. The purpose behind stinging is a compound response. It has a trichome that demonstrations like a hypodermic needle. Once reached the trichome breaks and deliveries the poisons like shellsol and calcium oxalate prompting tingling, agony, and aggravation for a few days. Along these lines stinging plants will be a treasury of important auxiliary metabolites. Tragia sort is generally celebrated for its stinging movement. T. involucrata is the most examined types of the family.

    Editorial Pages: 1 - 2

    Discovery and Resupply of Pharmacologically Active Plant-Derived Natural Products

    Zoya Genet

    Medical plants have verifiably demonstrated their incentive as a wellspring of atoms with remedial potential, these days actually address a significant pool for the ID of novel medication leads. In the previous many years, drug industry zeroed in predominantly on libraries of manufactured mixtures as medication disclosure source. They are equivalently simple to deliver and resupply, and show great similarity with set up high throughput screening (HTS) stages. Notwithstanding, simultaneously there has been a declining pattern in the quantity of new medications arriving at the market, bringing restored logical premium up in medication disclosure from normal sources, regardless of its known difficulties. In this study, a concise framework of chronicled advancement is given together a far reaching outline of utilized methodologies and ongoing improvements pertinent to plant-determined regular item drug disclosure. While the inborn intricacy of common item based medication disclosure requires profoundly coordinated interdisciplinary methodologies, the surveyed logical turns of events, late innovative advances, and exploration drifts unmistakably demonstrate that normal items will be among the main wellsprings of new medications additionally later on.

    Volume 7, Issue 2 (2021)

      Editorial Pages: 1 - 2

      Therapeutic Potential and Phytoconstituents of Allium cepa Linn

      Irene Adriano

      In the present scenario,  herbal medicines have gained global importance with both medicinal and economic implications. Widespread use of herbs all over the world has raised serious concerns over their quality, safety, and efficacy. Thus, accurate scientific assessment has become a prerequisite for the acceptance of health claims. Onion (Allium cepa Linn.) is a member of the genus Allium, is the second utmost important horticulture crop all over the world. It is used as an important source of phytoconstituents and food flavor. Onions are the richest sources of flavonoids and organosulphur compounds. They possess a high level of antioxidant activity attributable to flavonoids quercetin,  kaempferol,  myricetin;  pigments such as anthocyanins,  and organosulphur compounds.  The most important among the sulphur compounds are the cysteine derivatives non-volatile  S-amino acids,  S-alk(en)yl-substituted cysteine sulphoxides, and their decomposition products such as thiosulfinates and polysulfides. 

      Commentary Pages: 1 - 2

      Phytoestrogens in Postmenopausal Indications: A Theoretical Perspective

      Nouran Ahmad

      The estrogen, androgen, and progesterone receptors, individuals from the atomic receptor (NRs) superfamily, go about as atomic vehicle proteins, cell cycle parts, and record factors. Most cell activities of sex steroid chemicals are intervened through restricting to atomic receptors that go about as ligand-inducible record factors. Estrogen assumes a significant part in the development, separation, and capacity of numerous real targets, including the female and male conceptive frameworks. Estrogen likewise has an assortment of pharmacologic capacities, Estrogens (particularly estradiol) draw out the female attributes, control regenerative cycles and pregnancy, impact skin, resistance, support of bone mass, cardiovascular security, and mind protection. Estrogen lack during menopause can prompt danger for some medical conditions, like resting messes, vaginal dryness, joint agony, disposition swings, decreased bone thickness, cardiovascular infection, etc.

      Commentary Pages: 1 - 2

      Traditional uses and pharmacological Activity in Ferula asafoetida

      Sesuna Madihah

      Ferula asafoetida is a herbaceous plant of the Umbelliferae family. It is oleo gum sap to gain from the rhizome and base of the plant. The flavor is utilized as a stomach-related guide in food as fixing and in pickles and furthermore utilized in current herbalism in the treatment of delirium and some apprehensive conditions like bronchitis, challenging hack, and asthma. It was all at once utilized in the treatment of childish pneumonia and � pompous colic. The unstable oil in the gum is annihilated through the lungs, making this a great treatment for asthma. The scent of asafoetida is uncovered to the breath, emissions, � atus, and gastric eructations. The properties of it are antispasmodic, expectorant, energizer, emmenagogue, and vermifuge. It likewise diminishes the blood and brings down pulse and is broadly utilized in India in food and as medication like Ayurveda.

      Short Communication Pages: 1 - 2

      Neuroprotective potential of phytochemicals

      Kuntano Leonardo

      Psychological brokenness is a significant medical issue in the 21st century, and numerous neuropsychiatric issues and neurodegenerative problems, like schizophrenia, discouragement, Alzheimer's Disease dementia, cerebrovascular impedance, seizure issues, head injury and Parkinsonism, can be severly practically weakening in nature. In course of time, various synapses and flagging atoms have been identified which have been considered as restorative targets. Customary also more current particles have been attempted against these objectives. Phytochemicals from restorative plants assume a crucial part in keeping up the cerebrum's compound equilibrium by in� uencing the capacity of receptors for the major inhibitory synapses. In customary act of medication, a few plants have been accounted for to treat intellectual issues. In this survey paper, we endeavor to illuminate the utilization of therapeutic spices to treat intellectual problems.

      Short Communication Pages: 1 - 2

      Rubus fruticosus (blackberry) use as an herbal Medicine

      Christiano Evens

      Wild developed European blackberry Rubus fruticosus plants are far reaching in various pieces of northern nations and have been widely utilized in home grown medication. The outcome show that European blackberry plants are utilized for natural therapeutic reason like antimicrobial, anticancer, antidysentery, antidiabetic, antidiarrheal, and furthermore great cancer prevention agent. Blackberry plant (R. fruticosus) contains tannins, gallic corrosive, villosin, and iron; natural product contains nutrient C, niacin (nicotinic corrosive), gelatin, sugars, and anthocyanins and furthermore contains of berries egg whites, citrus extract, malic corrosive, and gelatin. Some chose physicochemical qualities, for example, berry weight, protein, pH, complete corrosiveness, solvent strong, lessening sugar, nutrient C, absolute cancer prevention agent limit, antimicrobial screening of natural product, leaves, root, and stem of R. fruticosus, and complete anthocyanins of four preselected wild developed European blackberry (R. fruticosus) natural products are examined. Sign cant contrasts on a large portion of the synthetic substance distinguish among the therapeutic use. Various cultivars filled in same area reliably show contrasts in cancer prevention agent limit.

      Volume 7, Issue 5 (2021)

        Editorial Pages: 1 - 1

        Introduction and Importance of Medicinal Plants and Herbs in Pharmacognosy

        Tankiso Sello

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        The expression "medicinal plant" incorporates different kinds of plants utilized in herbalism ("herbology" or "natural medication"). It is the utilization of plants for restorative purposes, and the investigation of such employments. "Spice" has been gotten from the Latin word, "spice" and an old French word "spice". Presently a day, spice alludes to any piece of the plant like natural product, seed, stem, bark, blossom, leaf, disgrace or a root, just as a non-woody plant. Prior, the expression "spice" was simply applied to non-woody plants, including those that come from trees and bushes. These therapeutic plants are likewise utilized as food, flavonoid, medication or aroma and furthermore in certain profound exercises. Plants have been utilized for restorative purposes well before ancient period. Old Unani original copies Egyptian papyrus and Chinese works portrayed the utilization of spices. Customary frameworks of medication keep on being broadly rehearsed on numerous records. Populace rise, deficient inventory of medications, restrictive expense of medicines, results of a few engineered medications and advancement of protection from as of now utilized medications for irresistible illnesses have prompted expanded accentuation on the utilization of plant materials as a wellspring of meds for a wide assortment of human diseases. As of late, WHO (World Health Organization) assessed that 80% of individuals overall depend on home grown meds for some part of their essential medical service’s needs. As per WHO, around 21,000 plant species have the potential for being utilized as therapeutic plants. Treatment with therapeutic plants is viewed as extremely protected as there is no or negligible results. These cures are in a state of harmony with nature, which is the greatest benefit. The brilliant certainty is that, utilization of home-grown medicines is autonomous of all age’s gatherings and the genders.

        Editorial Pages: 1 - 1

        COVID-19 Treatment Efforts Using Plant Technologies

        Raouda Neloumta

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        Covid-19 is a huge group of infections. A portion of the infections cause illnesses among people, while others among creatures like camels, steers, felines, and bats. A couple of creatures Covid-19 advance to contaminate people, like those that caused SARS, MERS, and COVID-19 flare-ups. Like other infections, the COVID-19 infection spreads through drops of spit or nasal release. Tainted people experience gentle to direct respiratory ailment and can recuperate without meds. Nonetheless, more seasoned patients with fundamental clinical concerns like coronary illness, diabetes, malignancy, hypertension, and ongoing respiratory infection are bound to create genuine sickness. Subsequently, researchers from different fields everywhere on the world are striving to concoct viable medicines to check the pandemic. Polymerase chain response (PCR) strategy is considered as the best quality level for illness diagnostics; be that as it may, it requires costly hardware and educated labor. In this manner, analysts at the University of Connecticut's Department of Biomedical Engineering built up the "Across the board Dual CRISPR-Cas12a" (AIOD-CRISPR), an ease, CRISPRbased demonstrative stage to distinguish irresistible sicknesses, including the COVID-19 infection. The CRISPR innovation is utilized in practically all creatures yet its initial applications were in plants. The AIOD-CRISPR test pack is expected for use at home or in little centers, decreasing infection transmission hazard. Contrasted with PCR, AIOD-CRISPR framework has better affectability and particularity. The test unit effectively recognized the DNA and RNA of SARS-CoV-2 and HIV. Western University and Suncor are creating serological test units for COVID-19 utilizing green growth as a creation plant for making the fundamental proteins for counter acting agent ID. Green growth are plant-like protists that possess amphibian conditions. Current tests depend on proteins created in creepy crawly or mammalian cells, which are costly and hard proportional. Green growth is a superior bio-processing plant elective since they are not difficult to develop and can be handily altered to create the viral proteins

        Commentary Pages: 1 - 1

        Synthesis of Condensed Tannins

        Mateneh Idris

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        The study of condensed tannins is among the oldest styles of chemistry famed. The origin of the word phenol springs from the apply that these compounds were employed in the animal skin trade. This trade has created use of tannins for hundreds of years. Tanning could be a method whereby dried animal skins are fashioned into animal skin by its contact with a copiousness of tannins. Within the Northern latitudes the foremost common phenol used was oak bark. The explanation for this was the big expanse of oaks that were a typical feature of all northern European countries within the past. This method had been dispensed for generations however the science behind the growth of animal skin chemistry was born out of the commercial Revolution. For the primary time animal skin was being made for over personal use and also the age of production had arrived throughout the evolution of this chemistry there are several pioneers WHO have gained a data of the advanced chemical processes concerned in tanning. The attainment of this information passed considerably on a trial-and-error basis. Consequently, there are several definitions that have tried to encapsulate verity essence of what defines a phenol. A general description used defines a phenol as everything extracted from a plant that offers a blue color on exposure to ferrous chloride. Haslam in his book on Plant Polyphenols prefers the definition coined by Bate-Smith and boyfriend, they projected that tannins were "water soluble phenoplast compounds having molecular weights between five hundred and three, 000 units which besides giving the same old phenoplast reactions, they need special properties, such as, the power to precipitate alkaloids, scleroprotein and alternative proteins."

        Commentary Pages: 1 - 1

        The Success of Natural Products in Drug Discovery

        Kidane Aaron

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        Natural items, including plants, creatures and minerals have been the premise of treatment of human infections. In any case, old astuteness has been the premise of current medication and will stay as one significant wellspring of future medication and therapeutics. Prior to twentieth century, unrefined and semi-unadulterated concentrates of plants, creatures, organisms and minerals addressed the lone drugs accessible to treat human and homegrown creature sicknesses. The twentieth century changed the speculation in the utilization of medications, as the receptor hypothesis of medication activity. As of late, there has been a recharged interest in regular item research because of the disappointment of elective medication disclosure techniques to convey many leads accumulates in key helpful regions like immunosuppression, against infectives, and metabolic illnesses. Regular items research keeps on investigating an assortment of lead structures, which might be utilized as layouts for the advancement of new medications by the drug business. There is no uncertainty that normal items have been, and will be, significant wellsprings of new drug compound

        Editorial Pages: 1 - 1

        Bacteria and Fungal Secondary Metabolite

        Toutou Naji

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        Colour affects equally of life, we have a tendency toll as together with} the garments we wear, the furnishings in our home, and also the attract of food. Just think, for example, however plants may prepare their own food while not pigment or however gas may well be carried within the body while not Hb. It may be aforementioned that life on earth depends on pigments. The use of pigments as colouring agents has been practiced since prehistoric times. Archaeologists have uncovered proof that early humans used paint for aesthetic functions. the utilization of pigment in prehistoric times was additional evidenced once pigments and grinding equipments, that were between 350,000 and four hundred,000 years previous, were found in an exceedingly cave at Twin Rivers, close to capital of Zambia, Zambia. Pigments were employed in completely different components of the planet. In Europe, it absolutely was practiced throughout the Bronze Age. In China, colouring with plants, barks, and insects has been derived back over five,000 years. In India, it occurred throughout the Indus vale amount (2500 BC). Henna was used before 2500 BC, whereas saffron has been mentioned within the Bible. In Egypt, mummies are found wrapped in coloured artefact, that showed the presence of pigment

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