Clinical Gastroenterology Journal

ISSN: 2952-8518

Open Access

Michael O’Grady

Department of General and Vascular Surgery, Otago University, Christchurch, New Zealand

  • Opinion Article   
    Statin Use and Risk of Acute Diverticulitis: A Population-Based Case-control Study
    Author(s): Michael O’Grady*, Louise Clarke, Gregory Turner, Matt Doogue, Frank Frizelle and Rachel Purcell

    Objective: To examine the association between statin use and the development of acute diverticulitis requiring hospital admission. Methods: A retrospective, population-based, case–control study was carried out on a cohort of adults, resident in Canterbury, New Zealand between 1-1-2003 and 31-1-2008, identified from the National Census; all identified cases were admitted to hospital and had CT confirmed diverticulitis. The positive control group comprised patients on nonaspirin non-steroidal anti-inflammatory drugs (NSAIDs), and the negative control group were patients on selective serotonin reuptake inhibitors (SSRIs). Medicine exposure was obtained from the Pharmaceutical Management Agency of New Zealand. Subgroup analysis was done by age and for complicated diverticulitis and recurrent diverticulitis. Results:.. Read More»
    DOI: 10.37421/cgj.2020.5.122

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