Open Access Articles On Clinical Immunology

Clinical immunologists are physicians who was the expert in the diagnosis and treatment of outpatients with outcome or acquired immune system defects that lead to infections and autoimmune complications (immunodeficiency disorders) and autoimmune diseases. immune systems and vasculitis where the body hurts.

The inflammatory responses induced by IgE upon contact with allergens in allergic rhinitis (AR) are associated with rapid alterations in the number of detectable circulating blood cells in a complete blood count (CBC). The aim of this study was to assess whether taking antihistamines could modulate the dynamics of allergen-induced CBC in male and female patients.
A total of N = 112 specific allergen challenges were performed in otherwise healthy RA subjects. Seventy-two (n = 72) subjects received placebo and forty (n = 40) received cetirizine (H1 receptor antagonist) orally before exposure to allergens in a double-blind randomized trial at the Vienna Challenge Chamber (VCC); a subgroup of twenty-five (n = 25) subjects received cetirizine and placebo on different study days (parallel group). Blood samples and symptom scores were taken at baseline and immediately after 6 h of respiratory challenge simulating contact with ambient allergens.
Females were associated with a pronounced increase in circulating monocytes (p <0.01) and males with a decrease in eosinophils (p <0.05) in the placebo group, but not in subjects treated with cetirizine. The significant increase in segmented neutrophils (p <.001) and the decrease in circulating erythrocytes (p <.01) during allergic challenge were less significant after taking cetirizine in both sexes.
Cetirizine inhibited the mobilization of neutrophils, lymphocytes and the decrease in the number of erythrocytes, but did not affect the increase in thrombocytes during an allergenic challenge. It further decreased the dynamics of gender-sensitive blood cells. Overall, as shown by a simple CBC, cetirizine critically decreased immediate and late innate immune responses following an allergen.

High Impact List of Articles

Conference Proceedings

Antibacterial Activities of Meroindenon and Merochlorins C, E and F, produced by a Marine-Derived Bacterium, Streptomyces sp.
Sojeong Kim
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Antibacterial Activities of Meroindenon and Merochlorins C, E and F, produced by a Marine-Derived Bacterium, Streptomyces sp.
Sojeong Kim
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
A 3 year review of UK NEQAS Parasitology’s EQA specimens containing multiple faecal parasites
Agatha Christie Santos Saez
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
A 3 year review of UK NEQAS Parasitology’s EQA specimens containing multiple faecal parasites
Agatha Christie Santos Saez
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Molecular characteristics of antimicrobial resistance and virulence determinants of Staphylococcus aureus isolates from clinical infection and food
Kui Luo
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Molecular characteristics of antimicrobial resistance and virulence determinants of Staphylococcus aureus isolates from clinical infection and food
Kui Luo
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Global warming: hot air or a real threat with no solution to be found on the internet
Jorg Imberger
Keynote: Medical Microbiology & Diagnosis
Global warming: hot air or a real threat with no solution to be found on the internet
Jorg Imberger
Keynote: Medical Microbiology & Diagnosis
Characterizing temporal and inter-individual functional differences in pre-term human infant gut microbiome development by a metaproteomics approach
R L Hettich, W Xiong, A Blakeley-Ruiz, C Brown, M Olm, M Rodgers, M J Morowitz and J F Banfield
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Characterizing temporal and inter-individual functional differences in pre-term human infant gut microbiome development by a metaproteomics approach
R L Hettich, W Xiong, A Blakeley-Ruiz, C Brown, M Olm, M Rodgers, M J Morowitz and J F Banfield
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis

Journal of Immunobiology