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6678 Blood Cancer Open Access | Open Access Journals
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Accounting & Marketing

ISSN: 2168-9601

Open Access

6678 Blood Cancer Open Access

Blood Cancer Journal is een internationaal, aan collegiale toetsing onderworpen open access wetenschappelijk tijdschrift op het gebied van de oncologie. De naam wordt in literatuurverwijzingen meestal afgekort tot Blood Canc. J. Het is opgericht in 2011 als zustertijdschrift van het gerenommeerde Leukemia en wordt uitgegeven door Nature Publishing Group.Blood Cancer Journal is een elektronisch tijdschrift; het verschijnt niet in druk. This article is about research into cancer, in general. For the UK-based charity, see Cancer Research UK. For the journal, see Cancer Research (journal). Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure.Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgeryradiation therapychemotherapyhormone therapyimmunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy.Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. Research into the cause of cancer involves many different disciplines including genetics, diet, environmental factors (i.e. chemical carcinogens). In regard to investigation of causes and potential targets for therapy, the route used starts with data obtained from clinical observations, enters basic research, and, once convincing and independently confirmed results are obtained, proceeds with clinical research, involving appropriately designed trials on consenting human subjects, with the aim to test safety and efficiency of the therapeutic intervention method. An important part of basic research is characterization of the potential mechanisms of carcinogenesis, in regard to the types of genetic and epigenetic changes that are associated with cancer development. The mouse is often used as a mammalian model for manipulation of the function of genes that play a role in tumor formation, while basic aspects of tumor initiation, such as mutagenesis, are assayed on cultures of bacteria and mammalian cells.

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