Microglial Mechanisms

Microglia/macrophages are the predominant immune cells concerned in the defence in opposition to mind damage. Their morphology and purposeful adjustments are correlated with the release of chance alerts prompted by means of stroke. those cells are normally responsible for clearing away useless neural cells and restoring neuronal capabilities. however, while excessively activated through the harm-associated molecular patterns following stroke, they could produce a massive quantity of proinflammatory cytokines that can disrupt neural cells and the blood-mind barrier and influence neurogenesis. those outcomes indicate the crucial roles of microglia/macrophages inside the pathophysiological approaches of stroke. however, the modifiable and adaptable nature of microglia/macrophages may also be useful for mind repair and no longer simply bring about harm. those awesome roles can be attributed to the distinctive microglia/macrophage phenotypes because the M1 populace is especially unfavorable, even as the M2 populace is neuroprotective. additionally, exclusive gene expression signature changes in microglia/macrophages had been discovered in various inflammatory milieus. these biofunctional functions enable dual roles for microglia/macrophages in brain damage and repair. currently, it's miles idea that the proper inflammatory milieu might also offer a suitable microenvironment for neurogenesis; however, certain mechanisms underlying the inflammatory responses that provoke or inhibit neurogenesis remain unknown. This assessment summarizes current development concerning the mechanisms involved in brain damage, restore and regeneration associated with microglia/macrophage activation and phenotype transition after stroke. We also argue that future translational studies need to be targeting multiple key regulating molecules to enhance brain repair, which have to be accompanied by way of the idea of a “healing time window” for sequential treatment plans.

High Impact List of Articles

Conference Proceedings

Whole-genome sequencing of a novel Chryseobacterium strain isolated from poultry feather waste
Adeline Lum Nde, Charimba G, Steyn L, Newman J D and Hugo C
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Whole-genome sequencing of a novel Chryseobacterium strain isolated from poultry feather waste
Adeline Lum Nde, Charimba G, Steyn L, Newman J D and Hugo C
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Phylogenetic diversity, antibiogram and plasmid profiling of enterotoxigenic Klebsiella variicola and Enterobacter species isolated from Iko River-Nigeria
Mmuoegbulam Augusta O, Belgini Daiani R B, Iroegbu Christian U, Brisibe Andy, Asikong Etta Bassey E and Oliveira Maia Valeria
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Phylogenetic diversity, antibiogram and plasmid profiling of enterotoxigenic Klebsiella variicola and Enterobacter species isolated from Iko River-Nigeria
Mmuoegbulam Augusta O, Belgini Daiani R B, Iroegbu Christian U, Brisibe Andy, Asikong Etta Bassey E and Oliveira Maia Valeria
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
New Cordyceps militaris strains by crossing single ascospores and PCR determination of their mating types
Byungjoo Lee
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
New Cordyceps militaris strains by crossing single ascospores and PCR determination of their mating types
Byungjoo Lee
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
POCUS: Approach to the patient using point-of-care ultrasound
Cesar Henriquez-Camacho
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
POCUS: Approach to the patient using point-of-care ultrasound
Cesar Henriquez-Camacho
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Occurrence of glanders in Fars and Alborz province in Iran and isolating Burkholderia mallei
Nader Mosavari, Rohollah keshavarz, Naheed Mojgani, Keyvan Tadayon, Shojaat Dashtipour and Mehdi Dehganpour
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Occurrence of glanders in Fars and Alborz province in Iran and isolating Burkholderia mallei
Nader Mosavari, Rohollah keshavarz, Naheed Mojgani, Keyvan Tadayon, Shojaat Dashtipour and Mehdi Dehganpour
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Molecular characterization of Staphylococus aureus isolated from Greek adults with Soft Skin Tissue Infections (SSTIs)
E Petinaki, S Mastraftsi, K Pantelidi, A Skoulakis and A Roussaki
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Molecular characterization of Staphylococus aureus isolated from Greek adults with Soft Skin Tissue Infections (SSTIs)
E Petinaki, S Mastraftsi, K Pantelidi, A Skoulakis and A Roussaki
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Prevalence of virulent and antibiotic resistant Klebseilla pneumoniae isolates among kidney stone patients from tertiary care hospital of Islamabad, Pakistan
Sahar Zafar, Saba Hanif and Rani Faryal
Scientific Tracks Abstracts: Journal of Antimicrobial Agents
Prevalence of virulent and antibiotic resistant Klebseilla pneumoniae isolates among kidney stone patients from tertiary care hospital of Islamabad, Pakistan
Sahar Zafar, Saba Hanif and Rani Faryal
Scientific Tracks Abstracts: Journal of Antimicrobial Agents
Community-acquired methicillin-resistant Staphylococcus aureus: Characteristics epidemiology, clinical, microbiology and molecular biology: SCCmec gene analysis and VISA in patients infected with Staphylococcus aureus an
Latre Buntaran
Scientific Tracks Abstracts: Journal of Antimicrobial Agents
Community-acquired methicillin-resistant Staphylococcus aureus: Characteristics epidemiology, clinical, microbiology and molecular biology: SCCmec gene analysis and VISA in patients infected with Staphylococcus aureus an
Latre Buntaran
Scientific Tracks Abstracts: Journal of Antimicrobial Agents

Journal of Immunobiology