Immunodeficiency Online Journal

Traditionally, primary immunodeficiency disorders (PID) have been described as diseases caused by one or more defects in the immune system, leading to increased susceptibility to infections. It is now known that PIDs are a group of heterogeneous disorders with abnormalities of the immune system characterized by various combinations of recurrent infections, autoimmunity, lymphoproliferation, granulomatous processes, atopy and malignancy. global is dictated by the specific type of underlying immune defect. Depending on the type of PID, the types of infections may vary. Although bacterial infections can be a key feature of B cell defects, infections with various pathogens (e.g., viruses, fungi and bacteria) are a hallmark of combined T and B cell immunodeficiencies. autoimmune manifestations can range from autoimmune cytopenia secondary to B cell defects to lupus erythematosus disseminated in complement disorders. Some PIDs (for example, X-linked lymphoproliferative disease) are characterized by lymphoproliferation while others (such as those associated with chronic granulomatous disease) are manifested by cutaneous, respiratory or gastrointestinal granulomas due to immune deregulation. Although lymphomas and leukemias are the most common malignancies, other types of tumors can also be seen. Atopic features such as asthma, atopic dermatitis and food allergies may be observed in some patients with T-cell abnormalities. Therefore, the types of manifestations and involvement of other systems may provide a clue to the PID type.

High Impact List of Articles

Conference Proceedings

Insights into xylan degradation and haloalkaline adaptation through whole-genome analysis of Alkalitalea saponilacus, an anaerobic haloalkaliphilic bacterium capable of secreting novel halostable xylanase
Baisuo Zhao, Ziya Liao, Mark Holtzapple, Yanchun Yan, Haisheng Wang and Jun Li
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Insights into xylan degradation and haloalkaline adaptation through whole-genome analysis of Alkalitalea saponilacus, an anaerobic haloalkaliphilic bacterium capable of secreting novel halostable xylanase
Baisuo Zhao, Ziya Liao, Mark Holtzapple, Yanchun Yan, Haisheng Wang and Jun Li
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Detection of androgenic-mutagenic compounds and potential autochthonous bacterial communities during in-situ bioremediation of hazardous distillery waste
Ram Chandra and Vineet Kumar
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Detection of androgenic-mutagenic compounds and potential autochthonous bacterial communities during in-situ bioremediation of hazardous distillery waste
Ram Chandra and Vineet Kumar
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Comparative assessment of probiotic attributes of Lactobacillus Plantarum strains of Ireland and Pakistan
Asma Manzoor, Javed Iqbal Qazi, Paul Ross, Johar Ali and Catherine Stanton,
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Comparative assessment of probiotic attributes of Lactobacillus Plantarum strains of Ireland and Pakistan
Asma Manzoor, Javed Iqbal Qazi, Paul Ross, Johar Ali and Catherine Stanton,
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
The human hand microbiome and effect of topical products
Sarah Wilson
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
The human hand microbiome and effect of topical products
Sarah Wilson
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Nasal colonization and antimicrobial susceptibility pattern of Staphylococcus aureus among pre-school children in Ethiopia
Alemayehu Reta
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Nasal colonization and antimicrobial susceptibility pattern of Staphylococcus aureus among pre-school children in Ethiopia
Alemayehu Reta
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis

Journal of Immunobiology