Journal of Coronary Heart Diseases

Open Access

Current Issue

Volume 3, Issue 2 (2019)

    Volume 4, Issue 1 (2020)

      Editorial Pages: 1 - 2

      Young Researchers Forum - Young Scientist Awards WHC 2020

      Dr. Suresh Vatsyayann

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      Editorial Pages: 1 - 1

      EDITORIAL NOTES OF Journal of Coronary Heart Disease

      Dr.William Sidney

      I am pleased to mention that during the year 2020, all issues of volume 4 were published online well within the time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. JCHD during this year also brought out a supplement to Jan-Feb 2020 issue, which consisted of 3 abstracts o. f an international conference on public health and hygiene. Besides JCHD also brought out an online special issue in 2020.JCHD is a leading journal among all journals in the field of Medical Science published in world .

      Volume 5, Issue 1 (2021)

        Research Pages: 1 - 2

        Cinnamon supplementation improved Blood pressure in type 2 diabetic patients: A systematic review and meta-analysis of randomized controlled trials

        Mohammad Jalali

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        Title: Cinnamon supplementation improved Blood pressure in type 2 diabetic patients: A systematic review and meta-analysis of randomized controlled trials


        Name: Mohammad Jalali

        Ronak Jalali

        Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.


        Hypertension is known as an important risk factor for cardiovascular diseases (CVD) and metabolic syndrome. Also some studies suggested a consumption of herbal medicine for improving them. The present systematic review and meta-analysis aimed to assess the efficacy of cinnamon supplementation on the improvement of blood pressure in type 2 diabetic patients. Systematic search was done in several online databases (PubMed, Embase, Scopus and Web of Sciences) to identify randomized controlled trials investigating the effect of cinnamon supplementation on systolic blood pressure (SBP) or diastolic blood pressure (DBP) for all potential publication up to 29 November 2019. Weighted mean difference (WMD) and 95% confidence interval (CI) were calculate to find the effect of cinnamon on the arms of this study. Potential publication bias was assessed using funnel plots and Egger weighted regression test. After excluding nonrelated records, 5 full-text articles included in this meta-analysis. Pooled results of the present meta-analysis on 332 participants indicated a significant reduction in SBP (WMD = -0.691, 95% CI = [-1.199, -0.182], P = 0.008) and DBP (WMD = -1.193, 95% CI = [-1.457, -0.930], P < 0.0001) following cinnamon administration. Also, no publication bias was found. The results of the present study suggested cinnamon for improving the blooad pressure in type 2 diabetic patients.



        Jalali is an Iranian nutritionist, which receive honorary doctorate as health education at the age of 20 years old and also has a traditional medicine certificate from Shiraz University of Medical Sciences with score 100. He is a member of Nutrition Research Center of Shiraz, Iran. He is specifically working on functional foods and nutraceuticals that can improve various metabolic disorders, and has obtained significant outcomes regarding important biomarkers.  He also eminence in the field of meta-analysis studies.


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        Editorial Pages: 1 - 1

        Coronary Angiography

        Mohd Anas Ansari

        Angiography or is a scientific technique used for the purpose of medical imaging to visualize and analyze the lumen of blood vessels, arteries, veins, and the heart chambers. It help for the detection and quantification of coronary artery disease, identification and other structural abnormalities, and measurement of hemodynamic parameters.

        Editorial Pages: 1 - 1

        Cardiac Arrhythmia

        Mohd Anas Ansari

        Cardiac arrhythmia is the condition which the heart normal rhythm is just disrupted. The heart pumps blood containing oxygen, nutrients, immune cells, and regulatory molecules to the body organs. The rhythm of the heart is set by a cardiac muscle cells in the right atrium called the Sinoatrial (SA) node that acts as a spontaneous pacemaker to maintain adequate blood pressure and oxygen.

        Editorial Pages: 1 - 1

        Congenital Heart Disease

        Mohd Anas Ansari

        A Congenital Heart Defect (CHD) is an anatomic abnormality of the heart or major vessels that develops during fetal development. The exact cause of all congenital cardiac defects is not known. Congenital cardiac disease affects about 8 out of every 1000 live births. A ventricular septal defect is the most frequent type of heart abnormality.

        Editorial Pages: 1 - 1

        Myocardial Infarction

        Mohd Anas Ansari

        The myocardial ischemia is a decrease of oxygen to the heart. This decrease can happen because of many reasons. One of the main reasons is the coronary artery disease. The myocardial ischemia is an acute shortage of blood supply to the myocardium, i.e the muscle of the heart. This decreases the oxygen supply to the muscle and causes the muscle to be unable to contract.

        Volume 5, Issue 5 (2021)

          Editorial Pages: 131 - 132

          Hyperkalemia in Heart Failure

          Mano likar

          Hyperkalemia is a not inconsistent clinical issue found in everyone. The genuine frequency is obscure yet is assessed to be in the 1%-10% territory. One justification for this is that there are changing meanings of hyperkalemia, with earlier investigations utilizing a potassium cut-off of more than 5.5 mEq/l or as high as 6 mEq/l to characterize hyperkalemia. As a general rule, hyperkalemia ought to be characterized as a serum potassium level of in excess of 5 mEq/l (or mmol/l).

          Editorial Pages: 128 - 129

          Aprepitant-Related Anaphylactic Shock and Cardiac

          Mano Likar

          The patient has been diagnosed with stage IV adenocarcinoma of the lung with adrenal gland, left internal iliac and pararectal lymph nodemetastases. Next generation sequencing was negative for actionablemutations, PDL 1 status 50%, Micro Satellite Instability (MSI-H) not detected. For bone metastases, she was started on IMPOWER 150, which included carboplatin+paclitaxel+bevacizum ab+atezolizumab+atezolizumab and zolendronic acid. The patient was taking mirtazapine, omeprazole, ondansetron, and albuterol at the same time at home.

          Editorial Pages: 129 - 130

          C Reactive Protein and Cardiovascular Disease

          Ketua Harris

          Cardiovascular Diseases (CVD) are the first reason for death in quite a while, subsequently it is important to lessen this general medical issue. The improvement of atherosclerosis is the primary driver of CVD. This pathology results from the amassing of lipids in the blood vessel divider that prompts a complex fiery cycle. Incendiary biomarkers are an important apparatus in the discovery and monitorization of the advancement of this interaction, just as in the decision of treatment to carry out. C-Reactive Protein (CRP), dictated by high affectability techniques (hs-CRP), is the most contemplated biomarker and stands apart among the others, being viewed as a significant marker of irritation.

          Editorial Pages: 126 - 127

          Myocardial Infarction with ST Elevation

          Mano likar

          Maintaining myocardial blood supply as soon as feasible is the most essential step in the treatment of ST elevation myocardial infarction. Thrombolytic therapy and percutaneous coronary intervention are the two most used treatments for myocardial reperfusion today. Reperfusion arrhythmias were studied to see if they were markers of coronary artery patency or if there was still ischemia following revascularization. The early trials of thrombolytic treatment guided revascularization in acute myocardial infarction used reperfusion arrhythmias.

          Editorial Pages: 127 - 128


          Ketua Haris

          Skeletal Muscle Cardiac Assist (SMCA) is gaining popularity as a viable surgical therapeutic option for end-stage heart failure. The muscle is wrapped around the heart and then triggered by electrical stimulation to increase cardiac contraction in one type, cardiomyoplasty. The hemodynamic effect of cardiomyoplasty has been the subject of a great deal of experimental and clinical research over the past decade. Over the last decade, a lot of experimental and clinical research has been done on the hemodynamic effects of cardiomyoplasty

          Volume 5, Issue 2 (2021)

            Commentary Pages: 1 - 1

            Tuberculosis and Risk of Acute Myocardial Infarction

            Mohd Anas Ansari

            Tuberculosis and Cardiovascular Disease (CVD) have a huge global impact. Tuberculosis and cardiovascular disease can not only occur at the same time, but they can also impact one another's risk. A direct effect of Mycobacterium TB on the heart and coronary arteries enhanced immune activation and cytokine production, and cross-reactivity of anti-mycobacterial antibodies against cardiovascular tissue are all possible contributions to CVD risk in tuberculosis. Several pathogens have been associated with increased cardiovascular disease (CVD) risk. Whether this occurs with Mycobacterium tuberculosis infection is unclear. Tuberculosis was linked to a higher incidence of AMI (adjusted Hazard Ratio (HR) of 198, 95 percent confidence intervals (CI) of 13-30). When the study was limited to pulmonary TB, the results were comparable Tuberculosis has been linked to a higher incidence of AMI.

            Editorial Pages: 1 - 1

            The Use of App-based Follow-up of Cardiac Implantable Electronic Devices

            Mohd Anas Ansari

            Although not all healthcare practitioners are on board with digital health, it is becoming more prevalent in the clinical setting. By providing creative methods to combine technology, connection, and people, modern technologies and digital appliances have a major influence on the way we care for patients. In the follow-up of these patients, remote monitoring and follow-up have shown to be superior to traditional treatment, and they have become the new standard of care. It focuses on patient empowerment and has yielded encouraging outcomes, but it also emphasises the need to improve the system's automaticity in order to achieve appropriate follow-up adherence rates. Patients who have cardiac implanted electronic devices must have device follow-up as part of their therapy (CIEDs). PPMs, ICDs,

            Editorial Pages: 1 - 2

            Progression of incomplete toward complete left bundle branch block

            Mohd Anas Ansari

            Cardiovascular mortality, sudden cardiac death, and heart failure are all linked to complete left bundle branch block (cLBBB). The appearance of cLBBB on an electrocardiogram (ECG) elevates clinical awareness and frequently necessitates additional cardiac investigations and clinical follow-up. Incomplete LBBB (iLBBB) is characterised by a QRS shape similar to cLBBB but with a QRS duration (QRSD) of less than 120 milliseconds. Patients with iLBBB have a poor clinical profile and a long natural history, hence their clinical profile and natural history are mostly unknown. The purpose of this study is to evaluate the clinical profile of iLBBB patients, the rate and risk factors for progression to cLBBB, and the outcome of iLBBB patients.

            Editorial Pages: 1 - 2

            Acute cardiac injury in patients with COVID-19

            Mohd Anas Ansari

            COVID-19's cardiac problems have the potential to be fatal. Myocardial damage is a multifactorial event in the setting of COVID-19 that has piqued researchers' curiosity. A systematic review of the literature was conducted, followed by a meta-analysis. The databases MEDLINE and EMBASE were combed. The publications were reviewed by two independent reviewers for the outcome of myocardial damage.

            Editorial Pages: 0 - 2

            Atrial Fibrillation

            Mohd Anas Ansari

            Atrial fibrillation is an irregular and often rapid heart rate that can increase your risk of strokes, heart failure and other heart-related complications. Symptoms often include heart palpitations, shortness of breath and weakness. Blood clots forming in the heart may circulate to other organs and lead to blocked blood flow (ischemia) Treatment may include medications and other interventions to try to alter the heart's electrical system. The heart's two upper chambers (the atria) beat chaotically and irregularly.

            Volume 5, Issue 3 (2021)

              Short Commentary Pages: 1 - 2

              Blood Pressure Targets for the Treatment of People with Hypertension and Cardiovascular Disease

              Antonio López

              Hypertension is a leading cause of early morbidity and mortality that can be avoided. People with hypertension and established cardiovascular disease are especially vulnerable; therefore lowering blood pressure below recommended levels could be beneficial. This technique has the potential to reduce cardiovascular mortality and morbidity, but it also has the potential to increase adverse events. In persons with hypertension and established cardiovascular disease, the ideal blood pressure target is uncertain. To see if 'lower' blood pressure targets (135 mmHg/85 mmHg) in the treatment of people with hypertension and a history of cardiovascular disease are associated with lower mortality and morbidity than' standard' blood pressure targets (140 mmHg to 160 mmHg/90 mmHg to 100 mmHg) in the treatment of people with hypertension and a history of cardiovascular disease (myocardial infarction, angina, stroke, peripheral vascular occlusive disease). High blood pressure is common in persons who have heart or vascular disorders. In those with a history of cardiac or vascular problems, certain clinical guidelines propose a lower blood pressure goal (135 mmHg/85 mmHg or lower) than in those without (normal blood pressure goals are 140 mmHg to 160 mmHg systolic and 90 mmHg to 100 mmHg diastolic). It's uncertain whether the reduced targets result in improved overall health.

              Editorial Pages: 109 - 110

              Genetic Basis for Congenital Heart Disease

              Amy Roberts

              This article presents a current overview of our understanding of genetic contributions to the development of congenital cardiac disease. Since the year 2007 the publication of a paper on the genetic basis of congenital heart disease, new genomic tools have been widely available, drastically altering our understanding of the aetiology of congenital heart disease. New molecular testing techniques are discussed, as well as their use to congenital cardiac disease, both alone and in combination with other congenital defects or syndromes. The latest research on copy number variations, syndromes, RASopathies, and heterotaxy/ciliopathies is presented. New research findings using congenital heart disease models. This review is expected to provide timely information on the genetic aspects of congenital heart disease to a wide range of health-care professionals, including paediatric cardiologists, paediatricians, adult cardiologists, thoracic surgeons, obstetricians, geneticists, genetic counsellors, and other related clinicians.

              Editorial Pages: 111 - 112

              Prevalence and Cardiovascular Health Impact on Family

              Quanhe Yang

              Despite lowering Cardiovascular Disease (CVD) death rates, heart disease remains the primary cause of death. Family history of heart disease is a significant risk factor that has long been linked to heart disease. The INTERHEART (Effect of Potentially Modifiable Risk Factors Associated with Myocardial Infarction) study was used to determine the relationship between Myocardial Infarction (MI) and parental history of MI. Shared genetic, environmental, and behavioural factors may contribute to an elevated risk of heart disease due to family history. With the early beginning of heart disease in the family and the number of persons affected, genetic factors play a larger role in the increased familial risk of heart disease. Genetic conditions, most commonly familial hypercholesterolemia, account for a small proportion of excess familial risk, but causes of most familial cases of heart disease remain unknown. Because a positive family history of early heart disease is a known risk factor for heart disease, it's crucial to assess its public health impact in terms of population prevalence of family history of heart disease, as well as the burden of heart disease attributed to family history. Because the survey is population-based, representative, and weighted, and collects information on heart disease, heart disease risk factors, and family history of premature heart disease, NHANES (The National Health and Nutrition Examination Survey) provides a unique opportunity to conduct such an analysis.

              Commentary Pages: 113 - 114

              Comparison of Lesion Characteristics between Conventional and High-Power Short-Duration Ablation using Contact Force-Sensing Catheter in Patients with Paroxysmal Atrial Fibrillation

              Van Ba

              For effective Atrial Fibrillation (AF) ablation, a transmural lesion must be created. In Contact Force-guided (CF) ablation for AF, the differences in lesion characteristics between conventional energy and High-Power Short-Duration (HPSD) settings remained unknown

              Brief Commentary Pages: 115 - 116

              Coronary Artery Disease

              Mc Cullough

              Coronary heart disease is the most common cause of death in the general population and in patients with ESRD. Both groups are subject to the same cardiovascular risk assessment and treatment approaches. Non-invasive coronary artery imaging has advanced, allowing for earlier diagnosis of subclinical disease. Medical care of coronary artery disease aims to alter the illness's natural course and alleviate angina symptoms. Despite the risks of stroke, myocardial infarction, and chest wound infection, coronary bypass surgery appears to be the preferred option in stable ESRD with multi vessel coronary artery disease.

              Volume 5, Issue 4 (2021)

                Editorial Pages: 114 - 115

                Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

                Lindsay Bond

                Thrombosis and inflammation may play a role in morbidity and mortality in coronavirus patients in 2019. Therapeutic-dose anticoagulation, we expected, would enhance outcomes in critically ill Covid-19 patients. Coronavirus disease 2019 (Covid-19) is linked to thrombosis and inflammation. Despite receiving standard-dose pharmacologic thromboprophylaxis, critically ill patients on Covid-19 are at increased risk of thrombosis. Systemic inflammation and coagulation activation indicators in circulation. As a result, inflammation and thrombosis may play a role in poor outcomes

                Editorial Pages: 116 - 117

                Health Factors and Risk of All-Cause, Cardiovascular, and Coronary Heart Disease Mortality

                Ricardas Radisauskas

                Despite recent declines in age-standardized death rates in high-income countries, Cardio Vascular Diseases (CVD), such as Coronary Heart Disease (CHD) and stroke, and cancer remain the leading causes of morbidity and mortality in the United States, most Western and Eastern countries, and the world. The decreases in CVD and other non-communicable disease mortality and morbidity can be linked to a variety of reasons, including improvements in modifiable risk factors. Recent findings from a number of studies have revealed the benefits of low levels of modifiable risk factors, also known as cardiovascular health factors, for all-cause mortality and CVD mortality or morbidity. Several studies, mainly in the US, have shown that alarmingly few adults participating in cohort studies achieved the favourable levels of all 7 most frequently measured CVD risk factors: physically activity, normal blood pressure, glucose and total cholesterol levels, body weight, and healthy diet.

                Editorial Pages: 118 - 119

                Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy

                Hasan Mahmoud

                Ischemic Heart Disease (IHD) is a major source of morbidity and mortality around the world. Ischemic Cardio Myopathy (ICM) is a late consequence of IHD that manifests as dilated cardiomyopathy with decreased cardiac function that is not entirely due to coronary artery occlusion or ischemic injury. To evaluate the clinical, electrocardiographic and echocardiographic profile of patients it needs to present with ischemic cardiomyopathy. In this cross sectional observational study 100 patients of ischemic cardiomyopathy admitted in hospital or visited OPD in NICVD, Dhaka from March’15 to Sept’15 were studied.

                Editorial Pages: 120 - 120

                Chronic Complications of Arteriovenous Fistulas for Hemodialysis

                Simpson Macleod

                Arterio Venous Fistulas (AVFs) for Hemo Dialysis (HD) have significant difficulties. HD vascular access should be of sufficient quality to allow for repeated puncture and a high blood flow rate for high-efficiency dialysis with minimal problems. The dialysis crew must be well-versed in the operation of the AVF, and corrective interventions should be rare. The construction of an AVF produces conditions that allow blood to flow more freely through the veins. Fulfilling these requirements lessens the likelihood of turbulence and endothelium injury, which reduces the probability of stenosis

                Editorial Pages: 122 - 123

                Role and Effective Therapeutic Target of Gut Microbiota in Heart Failure

                Ricardas Radisauskas

                Gut microbiota has been linked to a number of cardiovascular disorders in recent studies, with the study of gut microbiota and heart failure attracting particular interest. As a result, better understanding the function of gut microbiota in the formation and progression of heart failure would aid our understanding of the disease's pathophysiology and bring novel therapeutic options. Heart failure is a severe and fatal stage of many cardiovascular diseases, and it is an important aspect of global cardiovascular disease prevention and treatment

                Voume 3 Issue 1 (2019)

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