Journal of Coronary Heart Diseases

Open Access

Tuberculosis and Risk of Acute Myocardial Infarction


Mohd Anas Ansari

Tuberculosis and Cardiovascular Disease (CVD) have a huge global impact. Tuberculosis and cardiovascular disease can not only occur at the same time, but they can also impact one another's risk. A direct effect of Mycobacterium TB on the heart and coronary arteries enhanced immune activation and cytokine production, and cross-reactivity of anti-mycobacterial antibodies against cardiovascular tissue are all possible contributions to CVD risk in tuberculosis. Several pathogens have been associated with increased cardiovascular disease (CVD) risk. Whether this occurs with Mycobacterium tuberculosis infection is unclear. Tuberculosis was linked to a higher incidence of AMI (adjusted Hazard Ratio (HR) of 198, 95 percent confidence intervals (CI) of 13-30). When the study was limited to pulmonary TB, the results were comparable Tuberculosis has been linked to a higher incidence of AMI.


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