Journal of Immunobiology

Department of Anesthesiology and Critical Care Medicine, Freie Universität Berlin, Berlin, Germany

Publications

• Mini Review   
  Cutaneous Wound Healing By Antibodies to Injured Tissue
  Author(s): Jameson Frankel*
  
  The process of healing a wound involves an extremely well-ordered series of actions, including hemostasis, inflammatory cell infiltration, tissue regeneration, and remodelling. Following tissue destruction, wound healing occurs, thus we reasoned that antibodies might bind to injured tissues, facilitating the engulfment of damaged tissues by macrophages. Here, we demonstrate how B cells participate in wound healing by secreting antibodies against injured tissues. Transfer of spleen cells into splenectomized mice reversed the delay in wound healing caused by splenectomy. Additionally, splenectomized nude mice showed a delay in wound healing. Magnetic beads used to transfer enhanced B220+ cells sped up the healing process in mice with splenectomies. Magnetic beads used to transfer enhanced B220+ cells sped up the healing process in mice with splenectomies. Using a.. Read More»
  DOI: 10.37421/2476-1966.2022.7.183

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