The Vitamin B Complex Public Health Challenge

Cheryl Robertson^*
*Correspondence: Cheryl Robertson, Department of Public Health Administratio, University of Dhaka, Dhaka, Bangladesh, Tel: 7564925789, Email:

Editorial

There is general consensus that vitamin B complex supplementation during the periconceptional period substantially reduces the danger of ectoderm defects. This reduction in risk has led many health organisations to issue recommendations for ladies to require 0.4 mg of synthetic vitamin B complex daily additionally to consuming food folate from a varied diet. Three public-health strategies exist for reaching the recommended daily dose required for eff active prevention of defects: (1) women take supplements with vitamin B complex together with a healthy diet; (2) foods are fortified with synthetic vitamin B complex on a voluntary basis; and (3) a staple food is fortified on a compulsory basis.

After a brief overview of the preventive potential of vitamin B complex the most aim here is to review successes and failures of those three methods. Special emphasis is placed on population-based public-health interventions to stop ectoderm defects at the extent of communities and nations of particular interest are results published after mandatory fortification has been introduced in several countries. The folate status of the overall population in various countries also will be discussed. Folate is that the generic term for this water-soluble B-complex vitamin. It functions as a coenzyme in singlecarbon transfers within the metabolism of amino acids and nucleic acids. Vitamin B complex (pteroylmonoglutamic acid, or PGA) is that the most oxidised and stable sort of folate. It's the shape utilized in vitamin supplements and in fortified food products. Most present folates, called food folate are pteroylpolyglutamates. Dietary folate equivalents adjust for the nearly 50% lower bioavailability of food folate compared thereupon of synthetic vitamin B complex (PGA). Vitamin B complex plays a crucial part within the prevention of ectoderm defects and is suspected to stop another congenital anomalies and low birth weight, also as chronic diseases like disorder, cerebral stroke, cancer of varied sites, depression,3 dementia,4 and osteoporosis. Definite scientific evidence of a risk reduction in clinical trials is merely available for synthetic vitamin B complex and ectoderm defects.

Effect of vitamin B complex on risk of anomalies and disease

Two of the foremost common serious birth defects of the brain and spine are spinabifida and anencephaly. These ectoderm defects occur when a part of the ectoderm, which later develops into medulla spinalis and brain, doesn't close. Closing normally happens around 24 days after conception i.e., before the lady has realised that she is pregnant. within the case of anencephaly all infants are stillborn or die shortly after birth, whereas within the case of spinabifida, children survive with lifelong disabilities including paralysis, bowel and bladder incontinence, and other physical handicaps despite extensive medical and surgical care. Spinabifida prevalence is decided by time, region, and ethnicity.

Since diagnostic procedure results in the termination of a pregnancy in many cases, estimation of prevalence is difficult, especially in countries without national registration of pregnancy terminations thanks to ectoderm defects the most risk factors are a previous affected child or fetus, inadequate maternal intake of vitamin B complex, diabetes, use of Depokene or carbamazepine, obesity, and impaired vitamin B-12 status. Results of intervention studies10-12 have shown that periconceptional use of supplements with vitamin B complex alone, or multivitamins combined with vitamin B complex, can lower the danger of ectoderm defects by 0% to 80% at the present , primary prevention is merely possible through vitamin B complex supplementation and fortification.