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Complementary Medicine and Pharmacoeconomics |
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Open Access

Complementary Medicine and Pharmacoeconomics

Special Issue Article

Pages: 1 - 1

Evaluation of health care delivery, safety procedures, and canine welfare in an inpatient Animal-Assisted Therapy (AAT) program: A multicenter Failure Modes and Effects Analysis (FMEA)

Christian Tejeda*, Jeannette Meyer, Erin Rice, Kunal Wahi, Jennifer Dobkin, Dr. Megan Trieu, Dr. Daniel Karlin

Background: Growing evidence supports the use of animal-assisted therapy (AAT) as complementary therapy for various clinical conditions. In the academic literature, increasing evidence highlights utilization of AAT to address pain, anxiety, stress, depression, enhance mood, increase socialization, and increase energy levels. Currently, there is limited evidence-based practice research identifying and addressing areas of improvement within AAT programs. Our research aims to evaluate AAT at our institution using a Failure Modes and Effects Analysis (FMEA).
Methods: An FMEA is a tool for conducting a systematic analysis of a process in which potential risks may occur. For our study, we formed a multidisciplinary team and convened for 6 sessions to complete an FMEA table. Our research team reviewed, evaluated, and recorded failure modes pertaining to three process categories: health care delivery, safety procedures, and canine welfare. We devised improvements to prevent the identified failure modes.
Results: The process tree created consists of 8 subprocesses and 40 total steps or entries. The data analysis indicated 16 total failure modes, with RPNs ranging from 2 to 48 among which 4 failure modes fell within the “very high” risk category with RPNs greater than 40. The data analysis indicated that the two failure modes with the highest RPNs included failure to complete request list (RPN: 48) and canine contamination of injection site(s) (RPN: 48).
Discussion: For half of 16 failure modes, we found improving the program’s orientation and training process to be an appropriate preventative action. We will continue conducting evaluations of every failure mode at 3, 6, and 12-month time points. These results bear importance to a better understanding of the current challenges and improvement opportunities for inpatient AAT. One limitation of the study was the relatively small size of the research team which could have included more agents within the overall process.

Special Issue Article

Pages: 2 - 2

Evaluation of Pistacia vera L. efficacy (Syrian traditional medicine) as adjuvant treatment for Cutaneous Leishmaniasis

Chadi Khatib

Our search has mainly focused on the use of the traditional dermal cream that consists of an extract of pistachio fruit peels and its tree gum as adjuvant treatment of Cutaneous Leishmaniasis. Pistacia vera L. is a plant of Syrian origin, and the oldest tree of this plant exists in Al-Qalamoun area in Rural Damascus in Syria. As the peels of Pistacia vera L. fruits and the gum of its tree are rich with the phenolic substances. Cutaneous Leishmaniasis is seen in more than 80 countries all over the world and the Mediterranean region is considered one of the most affected areas with this epidemic, knowing that Aleppo is historically considered the home for this disease and that's why, this disease is called "Aleppo Boil", the spread of this epidemic has markedly increased in the world. There is no vaccine for Leishmaniasis and the available chemical treatment, that includes several ant parasites such as the Pentium-equivalent antimony derivatives including antimoniate meglumene and sodium stibogluconate has several limitations including among others, its variable efficacy depending on the type of parasite and the potential resistance for it, its high toxicity for the liver and heart, the long treatment duration and its high cost. Due to the above-mentioned facts, the drugs co-treatments (chemical-chemical) is getting more consideration. Besides, the natural products have recently become an unlimited source for developing anti Leishmania drugs given that they provide better level of efficacy and safety along with lower levels of toxicity in addition to their lower cost. We have assessed the efficacy of the ethanolic extracts of Pistacia vera as anti-Leishmaniasis in both in vitro and clinical study through topical administration.
The in-vitro tests were conducted using the ethanolic extracts of Pistacia vera tree's gum and the L.tropica parasites viability. The results showed a good biological effect when treating the parasites with gradually increased concentrations of the ethanolic extracts during the 48 hours of incubation. The double- blinded clinical study was conducted on 102 patients at the Leishmania center in Aleppo. The clinical results and observations showed that the local complementary treatment with the extracts of both the skin peels of Pistacia vera L. fruits and the gum of Pistacia vera L. tree could support the chemical treatment with antimoniate meglumene (administered through local injection) in treating the Cutaneous Leishmaniasis. The above mentioned support is manifested with reducing the injured area and its hardness in addition to reducing the edema and the redness. Besides, the above mentioned extracts could significantly support the treatment of the secondary infection and its associated ulcer.

Special Issue Article

Pages: 3 - 3

Rediscovering herbal contraceptives in Ayurveda - Windows of research via ethnopharmacological research

Charu Sharma *, Sujata Kadam, Meenakshi Pandey

In the time you read the title , there would have been 4 live-births around the globe. 210 million pregnancies occur worldwide each year, of which, 40% are un palnned. Current researches are centred around immunocontraceptives, molecular condoms but there is an immense quest for completely safe and used friendly contraceptive. Ethnopharmacological-Driven Drug Development becomes the need of the hour to establish noble solutions for global concerns. This review article is a methodology to analyze the pharmacological aspect of contraceptives along with evaluating the current scenario of researches in the drug development process of contraceptives. This article summarizes the results of various classical references and researches related to drug discoveries of contraceptives. This artcle deals with future leads to herbal contraceptives and presents an interdisciplinary model of research.

Special Issue Article

Pages: 4 - 4

Holistic interventions in Ayurveda for a healthy progeny

Charu Sharma

Prenatal care is known as “garbhini paricharya” in Ayurveda. ‘Garbhini’ means pregnant woman and ‘paricharya’ means ideal protocol. It includes the ideal dietary and lifestyle protocol followed by a pregnant woman to attain optimum health of progeny and prevent any complications. The guidelines for prenatal care start even before conception. The couple planning to have a progeny shall follow purification procedures (panchakarma), proper diet and life style modifications as part of preconception care. The prenatal care begins from the very first day when the woman expects the conception (usually due to missed menstrual cycle). The conceived woman shall be treated with special care just like a pot filled with oil. As the slightest oscillation of such a pot causes spilling of the oil, similarly the slightest exertions or excitements to the pregnant woman can initiate adverse pregnancy outcomes.

Special Issue Article

Pages: 5 - 5

Natural Anamorphosis Process

Alexandros Senarelis-Sinaris

With the deepest respect to the human imperfect, Natural Anamorphosis Process operates non-aggressively towards the cryptoalgorithm of any form of problem and the noisy, foggy, obfuscating dynamics of its potential complications. With the physio-logical tactic of its centrifugal approach, moves peripherally and in between (neutral behavior) the event horizons of the healthy bio-available and any pathology, disease, illness, syndrome, injury etc, which is basically the "abstract" area of the emerging stress before the true values-1 (biophotons-light-energy-electricity-3D holographic & elctromagnetic fields) inevitably become false values-0 (nihilism). With the introduction and the usage of valuable and complex information (informational medicine) of undoubtedly rigorous sciences such as mathematics, physics, biology and philosophy, NAP as a regulator/buffer aims for the least action path (Hamilltonian physics) and with the controlled repetition (enrgams) of its intentional systems & agents, intends to maintain and enhance the physio-logical mechanisms of homeostasis and, by extension, through the parasympathetic system (vagus nerve-interoception) the stored energy levels of healthy bioavailability, since they form the absolute natural intrinsic self repair mechanism of smoothness and existence (Navier-Stokes). NAP is an innocuous Salutogenic (health-stress-coping) neuro-based independent Naturopathic system with neutral behavior. Neuronal stimulation (e.g transdermal, transensory) is an emerging field in modern medicine. As neuronal networks were evolutionarily selected to achieve physiological homeostasis, it is not surprising that neuromodulation emerged as one of the first strategies used in medicine to reestablish homeostasis during illness. Scientific studies indicate that the design of novel non-invasive techniques for nerve stimulation can help control immune and organ functions. NAP is based purely on the logic behind the mathematical symmetric property of equality, by creating simple models of complex bio-logical neuro-behavioral organic algorithms (simplexity). So when therapy by definition aims to normalize a distorted biological condition, actually what it does is to try to bring biochemical regularity (normal functioning). Now if we see it from another perspective (Anamorphosis), by intensifying or enduring the normal bio-available functioning (eurythmia), essentially we are in a therapeutic sphere of influence via a simple reverse process thinking mechanism (logic).

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