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Environmental Factors Influencing Thyroid Health: A Global Perspective
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Reports in Thyroid Research

ISSN: 2684-4273

Open Access

Opinion - (2025) Volume 9, Issue 1

Environmental Factors Influencing Thyroid Health: A Global Perspective

Zara Jordan*
*Correspondence: Zara Jordan, Department of Public Health, Healthcare Policy, Clinical Research, Qatar University, Al Tarfa, Doha, Qatar, Email:
Department of Public Health, Healthcare Policy, Clinical Research, Qatar University, Al Tarfa, Doha, Qatar

Received: 03-Mar-2025, Manuscript No. rtr-25-164101; Editor assigned: 05-Mar-2025, Pre QC No. P-164101; Reviewed: 17-Mar-2025, QC No. Q-164101; Revised: 24-Mar-2025, Manuscript No. R-164101; Published: 31-Mar-2025 , DOI: 10.37421/2684-4273.2025.9.104
Citation: Jordan, Zara. “Environmental Factors Influencing Thyroid Health: A Global Perspective.” Rep Thyroid Res 09 (2025): 104.
Copyright: © 2025 Jordan Z. This is an open-access article distributed under the terms of the creative commons attribution license which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Introduction

Thyroid health is influenced by a wide range of environmental factors that vary across different regions and populations worldwide. While genetic predisposition plays a significant role in thyroid function, external factors such as diet, exposure to toxins, climate and lifestyle choices can also have a profound impact on thyroid health. The thyroid gland, responsible for regulating metabolism through the production of thyroid hormones, is highly sensitive to changes in the environment. For instance, iodine deficiency an environmental factor is one of the leading causes of thyroid disorders globally, particularly in areas where iodine-rich foods are scarce. Similarly, exposure to endocrine-disrupting chemicals, such as pesticides and industrial pollutants, has been linked to thyroid dysfunction, especially in regions with high levels of environmental contamination. The global perspective on thyroid health highlights the interplay between environmental factors and regional variations in thyroid disease prevalence. In some areas, the introduction of iodized salt has significantly reduced the incidence of iodine deficiency, while other regions continue to struggle with environmental contaminants that negatively impact thyroid function. Furthermore, the growing body of research on climate change and its potential effects on thyroid health adds a new layer of complexity to understanding these environmental influences. This introduction will explore the various environmental factors that influence thyroid health on a global scale, examining how geography, lifestyle and environmental exposures contribute to thyroid disorders and disease prevalence [1].

Description

Environmental factors play a critical role in shaping thyroid health, with influences ranging from diet and lifestyle to exposure to pollutants and climate. The thyroid gland, which regulates metabolism and energy balance through thyroid hormones, is particularly vulnerable to environmental changes. One of the most well-known environmental factors affecting thyroid function is iodine deficiency. Iodine is essential for thyroid hormone production and in regions where iodine is lacking in the diet, individuals are at higher risk for thyroid disorders like goiter and hypothyroidism. To address this, many countries have implemented iodine fortification programs, such as iodized salt, which have significantly reduced the prevalence of iodine deficiency-related thyroid diseases. In addition to iodine, other environmental exposures have been shown to disrupt thyroid function. Endocrine-Disrupting Chemicals (EDCs) found in pesticides, plastics and industrial pollutants can interfere with thyroid hormone production and metabolism. These chemicals can mimic or block the action of natural hormones, potentially leading to thyroid dysfunction. High levels of EDCs in the environment are particularly concerning in industrialized regions and urban areas, where pollution levels tend to be higher [2].

Environmental factors play a significant role in influencing thyroid health, with numerous studies showing that exposure to specific toxins, chemicals and lifestyle factors can disrupt thyroid function. One of the most well-known environmental influences is iodine deficiency, which remains a global issue, particularly in regions with limited access to iodine-rich foods or salt. Iodine is an essential element required for the production of thyroid hormones and its deficiency can lead to conditions such as goiter and hypothyroidism. In addition to iodine, other environmental factors, such as exposure to Endocrine- Disrupting Chemicals (EDCs) like pesticides, heavy metals and certain plastics, can interfere with thyroid function. These substances may mimic or block the action of thyroid hormones, leading to altered thyroid activity, particularly in vulnerable populations such as pregnant women and young children [3].

Climate change and pollution are also emerging as important environmental factors that can impact thyroid health globally. Research has shown that air pollution, particularly fine Particulate Matter (PM 2.5), can negatively affect thyroid function by increasing oxidative stress and inflammation in the body. Furthermore, the global increase in industrial chemicals, such as per- and Polyfluoroalkyl Substances (PFAS), has raised concerns about their role in disrupting thyroid hormone production. These chemicals accumulate in the environment and the human body, potentially leading to long-term thyroid dysfunction. Additionally, lifestyle factors such as diet, stress and exposure to radiation also contribute to thyroid health, highlighting the need for comprehensive strategies to mitigate environmental risks and promote public awareness regarding thyroid disease prevention. Addressing these environmental factors is essential for improving global thyroid health and reducing the incidence of thyroid-related disorders worldwide [4].

Dietary factors also play a significant role, as certain foods and nutrients can either support or hinder thyroid function. For example, excessive consumption of goitrogens compounds found in foods like cruciferous vegetables, soy and cassava can interfere with iodine absorption and thyroid hormone production, especially in individuals with low iodine intake. On the other hand, a diet rich in selenium, zinc and other micronutrients supports thyroid health by helping to maintain proper hormone function. Climate change is another emerging environmental factor with potential consequences for thyroid health. As climate patterns shift, regions that experience changes in temperature, food availability, or water sources may face increased risks of nutrient deficiencies, including iodine and exposure to new environmental contaminants. Understanding how these environmental factors interact with thyroid function on a global scale is essential for improving public health policies and prevention strategies. Overall, a global perspective on environmental factors influencing thyroid health reveals the complex and interconnected ways in which our surroundings impact thyroid function. By addressing factors such as iodine deficiency, environmental pollutants and diet, we can better manage and prevent thyroid disorders around the world [5].

Conclusion

In conclusion, environmental factors play a significant role in influencing thyroid health, with iodine deficiency, exposure to endocrine-disrupting chemicals, dietary habits and climate change being key contributors. The global prevalence of thyroid disorders varies greatly depending on regional environmental conditions, such as iodine intake and pollution levels. While progress has been made in addressing issues like iodine deficiency through iodization programs, other environmental challenges, such as exposure to harmful chemicals and changing climates, continue to pose risks to thyroid health worldwide. Understanding these environmental influences is crucial for developing effective public health strategies, improving prevention efforts and ensuring better management of thyroid disorders on a global scale.

Acknowledgment

None.

Conflict of Interest

None.

References

  1. Zeber-Lubecka, Natalia and Ewa E. Hennig. "Genetic susceptibility to joint occurrence of polycystic ovary syndrome and Hashimoto’s thyroiditis: How far is our understanding?." Front Immunol 12 (2021): 606620.

    Google Scholar, Crossref, Indexed at

  2. Purcell, Shaun, Benjamin Neale, Kathe Todd-Brown and Lori Thomas, et al. "PLINK: A tool set for whole-genome association and population-based linkage analyses." Am J Hum Genet 81 (2007): 559-575.

    Google Scholar, Crossref, Indexed at

  3. Hynes, Kristen L., Petr Otahal, Ian Hay and John R. Burgess. "Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the gestational iodine cohort." J Clin Endocrinol Metab 98 (2013): 1954-1962.

    Google Scholar, Crossref, Indexed at

  4. Neumann, Susanne, Bruce M. Raaka and Marvin C. Gershengorn. "Human TSH receptor ligands as pharmacological probes with potential clinical application." Expert Rev Endocrinol Metab 4 (2009): 669-679.

    Google Scholar, Crossref, Indexed at

  5. Kasiyan, Olha, Halyna Tkachenko, Natalia Kurhaluk and Svitlana Yurchenko, et al. "Relationship between thyroid hormonal status in patients with a hypothyroid form of hashimoto’s thyroiditis and iodine concentrations in drinking water." Biol Trace Elem Res 200 (2022): 59-66.

    Google Scholar, Crossref, Indexed at

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