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Open Access Journals On Ichthyosis Vulgaris | Open Access Journals
International Journal of Public Health and Safety

International Journal of Public Health and Safety

ISSN: 2736-6189

Open Access

Open Access Journals On Ichthyosis Vulgaris

Ichthyosis vulgaris is caused by mutations in the debt of duty  of the filaggrin DNA (FLG) and is characterized clinically by xerosis, flaking, keratosis pilaris, palmar and plantar hyperlinearity and a strong association with atopic disorders. According to the published studies presented in this review article, FLG mutations are seen in approximately 7.7% of Europeans and 3.0% of Asians, but appear to be uncommon in dark-skinned populations. This clinical review article provides an overview of the epidemiology of common ichthyosis, associated disorders and pathological mechanisms. Not only does  anthesis vulgaries have a chick  clinical spectrum, but new review suggest that carriers of FLG mutations may have a generally altered risk of developing common diseases, even beyond atopic disorders. Modernistic studies have exposed expanded infiltration penetration of  dander and vinegar into filaggrin deficient skin, and epidemiological studies have found higher levels of hand eczema, irritant contact dermatitis, nickelhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317863/ sensitization and levels vitamin D serum levels. If appropriate, individuals should be informed of an increased risk of developing dermatitis when they are repeatedly or continuously exposed to nickel or irritants. In addition, with our current knowledge, people with ichthyosis vulgaris should be protected from neonatal exposure to cats to prevent atopic dermatitis and should refrain from smoking to prevent asthma. Finally, they should be discouraged from excessive exposure to factors that decrease the skin barrierhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317863/ functions and increase the risk of atopic dermatitis.

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