Ichthyosis vulgaris is caused by mutations in the debt of duty of the filaggrin DNA (FLG) and is characterized clinically by xerosis, flaking, keratosis pilaris, palmar and plantar hyperlinearity and a strong association with atopic disorders. According to the published studies presented in this review article, FLG mutations are seen in approximately 7.7% of Europeans and 3.0% of Asians, but appear to be uncommon in dark-skinned populations. This clinical review article provides an overview of the epidemiology of common ichthyosis, associated disorders and pathological mechanisms. Not only does anthesis vulgaries have a chick clinical spectrum, but new review suggest that carriers of FLG mutations may have a generally altered risk of developing common diseases, even beyond atopic disorders. Modernistic studies have exposed expanded infiltration penetration of dander and vinegar into filaggrin deficient skin, and epidemiological studies have found higher levels of hand eczema, irritant contact dermatitis, nickelhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317863/ sensitization and levels vitamin D serum levels. If appropriate, individuals should be informed of an increased risk of developing dermatitis when they are repeatedly or continuously exposed to nickel or irritants. In addition, with our current knowledge, people with ichthyosis vulgaris should be protected from neonatal exposure to cats to prevent atopic dermatitis and should refrain from smoking to prevent asthma. Finally, they should be discouraged from excessive exposure to factors that decrease the skin barrierhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317863/ functions and increase the risk of atopic dermatitis.
Market Analysis: International Journal of Public Health and Safety
Market Analysis: International Journal of Public Health and Safety
Review Article: International Journal of Public Health and Safety
Review Article: International Journal of Public Health and Safety
Research Article: International Journal of Public Health and Safety
Research Article: International Journal of Public Health and Safety
Short Communication: International Journal of Public Health and Safety
Short Communication: International Journal of Public Health and Safety
Posters & Accepted Abstracts: Journal of Nursing & Care
Posters & Accepted Abstracts: Journal of Nursing & Care
Scientific Tracks Abstracts: Journal of Nursing & Care
Scientific Tracks Abstracts: Journal of Nursing & Care
Posters & Accepted Abstracts: Journal of Nursing & Care
Posters & Accepted Abstracts: Journal of Nursing & Care
Scientific Tracks Abstracts: Journal of Nursing & Care
Scientific Tracks Abstracts: Journal of Nursing & Care
Posters-Accepted Abstracts: Journal of Nursing & Care
Posters-Accepted Abstracts: Journal of Nursing & Care