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Molecular Diagnosis Of Pathogens | Open Access Journals
Molecular Biology: Open Access

Molecular Biology: Open Access

ISSN: 2168-9547

Open Access
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Molecular Diagnosis Of Pathogens

Molecular diagnostics of bacterial pathogens is a rapidly growing field within clinical microbiology. The first commonly used routine application was the detection of bacterial sexually transmitted pathogens. Most of these micro-organisms are difficult to culture and therefore molecular diagnostics are providing a reliable, easy and high-throughput alternative. Over time, molecular diagnostic methods were developed and implemented for more easily culturable micro-organisms as well. The implementation of molecular tests for detection of bacterial gastrointestinal pathogens is one example that is discussed in this chapter. In this latter area often a combination of molecular diagnostics with conventional culture is preferred. Until the last decade, the methods employed in clinical laboratories involved natural amplification in culture, requiring viable pathogens and a relatively extended time period, usually at least overnight, for replication to the limit of detection.

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