Mass spectrometry mainly helps in measurement of protein mass, protein identity as well as quantification with high speed and accuracy. Also analyses other molecules such as lipids, glycans and oligonucleotides. This technique breaks proteins into peptides. This technique even studies the protein catalytic activity. Developments in mass spectrometry have simultaneously decreased the cost and increased the resolution and flexibility of these instruments. Advances in data processing have enabled the high-throughput analysis of mass spectra. In order to analyse the molecules by mass-spectrometry creation of gas phase ions is a must criteria. The two commonly used methods in mass spectrometry are: MALDI (Matrix-assisted laser desorption) which ionizes molecules cocrystallized with an organic matrix followed by a photoinonization process for ionization of analyte. Ions produced initially as singly proyonated molecules and in combination with a time-of-flight (TOF) mass spectrometer the sensitivity is in low range.
Related Journals of Mass Spectrometry Molecular Biology
Journal of Analytical and Bioanalytical Techniques, Journal of Mass Spectrometry, International Journal of Mass Spectrometry, European Journal of Mass Spectrometry, Mass Spectrometry Letters, Journal of Chinese Mass Spectrometry Society.