Molecular Biology: Open Access

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Development of Fluorescent Carbon Dots for Selective and Sensitive Detection of Copper Ions and Cellular Imaging

Maximiliano Hart*

DOI: 10.37421/2168-9547.2024.14.480

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Fluorescent Carbon Dots (CDs) have emerged as a versatile tool in nanotechnology due to their superior optical properties, biocompatibility and ease of synthesis. They are increasingly used for sensing applications, including the detection of metal ions such as copper, which is crucial for various biological and environmental processes. The ability to selectively and sensitively detect copper ions (Cu² ) is important for both practical and research applications. This study aims to develop advanced fluorescent carbon dots specifically designed for the selective and sensitive detection of copper ions. Additionally, the application of these CDs in cellular imaging is explored to demonstrate their utility in biological contexts. The CDs were synthesized via a hydrothermal method, optimized to enhance their fluorescence and selectivity towards copper ions. The materials were characterized using techniques such as UV-Vis spectroscopy, photoluminescence spectroscopy, Transmission Electron Microscopy (TEM) and Dynamic Light Scattering (DLS). The performance of the CDs in detecting copper ions was evaluated under various conditions and their potential for cellular imaging was assessed using fluorescence microscopy on live cells. The synthesized CDs exhibited high fluorescence quantum yields, stability and selectivity towards copper ions. The detection of copper ions was achieved with high sensitivity, reaching low detection limits. Cellular imaging demonstrated that the CDs could effectively label copper ions within live cells, providing clear visualization of copper distribution. The developed fluorescent carbon dots represent a significant advancement in sensing and imaging technologies. Their high selectivity and sensitivity for copper ions, coupled with their biocompatibility, make them a promising tool for environmental monitoring and biomedical research.

Brief Report Pages: 1 - 2

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Leila Ahmed*
DOI: 10.37421/2168-9547.2025.14.480
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Cellular Ballet: Orchestrated Molecular Dynamics Within Cells
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DOI: 10.37421/2168-9547.2025.14.481
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Commentary Pages: 1 - 2

Cellular Life: Molecular Mechanisms And Their Significance
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DOI: 10.37421/2168-9547.2025.14.482
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Cellular Communication: Orchestrating Life's Dynamic Networks
Sophia Muller*
DOI: 10.37421/2168-9547.2025.14.483
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Opinion Pages: 1 - 2

Molecules: The Orchestrators of Life and Disease
Carlos Fernandez*
DOI: 10.37421/2168-9547.2025.14.484
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Cellular Life: Molecular Mechanisms, Processes, and Therapeutics
Mikhail Ivanov*
DOI: 10.37421/2168-9547.2025.14.485
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Perspective Pages: 1 - 3

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DOI: 10.37421/2168-9547.2025.14.486
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DNA: Architect of Life, Genome Dynamics, and Regulation
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DOI: 10.37421/2168-9547.2025.14.487
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Molecular Architectures: Basis of Life and Health
Isabelle Fournier*
DOI: 10.37421/2168-9547.2025.14.490
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Gene Expression and Protein Localization Drive Cellular Function
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DOI: 10.37421/2168-9547.2025.14.491
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Cellular Fate: Orchestration of Molecular Networks
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DOI: 10.37421/2168-9547.2025.14.492
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DOI: 10.37421/2168-9547.2025.14.493
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DOI: 10.37421/2168-9547.2025.14.494
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Genetic Code: Orchestrating Brain Molecular Mechanisms and Disorders
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DOI: 10.37421/2168-9547.2025.14.495
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Molecules in Motion: Dynamics of Cellular Life
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DOI: 10.37421/2168-9547.2025.14.496
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Intermolecular Forces: Orchestrating Life's Fundamental Processes
David Rosenberg*
DOI: 10.37421/2168-9547.2025.14.497
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Molecular Biology: Discoveries for Therapeutics and Diagnostics
Oliver Green*
DOI: 10.37421/2168-9547.2025.14.500
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Molecular Machinery: The Cell's Essential Operations
Radhika Patel*
DOI: 10.37421/2168-9547.2025.14.501
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Cellular Mechanisms: Aging, Longevity, and Disease Therapeutics
Paula Silva*
DOI: 10.37421/2168-9547.2025.14.502
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Genes, Proteins, and Cellular Health: A Molecular Biology Exploration
Matthias Becker*
DOI: 10.37421/2168-9547.2025.14.503
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Cellular Narratives: DNA, RNA, Proteins, and Memory
Veronica Perez*
DOI: 10.37421/2168-9547.2025.14.504
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Cellular Empires: Molecular Architecture and Dynamics Unveiled
Tomas Alvarez*
DOI: 10.37421/2168-9547.2025.14.505
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Cellular Stories: Molecular Processes and Metaphors
Clara Richter*
DOI: 10.37421/2168-9547.2025.14.506
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Cellular Life: Molecular Mechanisms and Homeostasis
Satoshi Yamamoto*
DOI: 10.37421/2168-9547.2025.14.507
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Molecules of Life: Building Blocks of Biology
Charlotte Jackson*
DOI: 10.37421/2168-9547.2025.14.510
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Molecular Foundations: Life's Origins, Universality, and Beyond
Cheng Li*
DOI: 10.37421/2168-9547.2025.14.511
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Molecular Spells: The Science of Life Processes
Robert Klaus*
DOI: 10.37421/2168-9547.2025.14.512
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Molecular Forces: Key to Life and Disease
Patricia Gomez*
DOI: 10.37421/2168-9547.2025.14.513
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Molecular Commands Governing Cellular Life and Function
Luca Rossi*
DOI: 10.37421/2168-9547.2025.14.514
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The Molecular Symphony: Orchestrating Cellular Life
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DOI: 10.37421/2168-9547.2025.14.515
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Molecular Guardians: Safeguarding Cellular Health and Preventing Disease
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DOI: 10.37421/2168-9547.2025.14.516
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Cellular Dynamics: Molecular Transformations for Life
Benjamin Fischer*
DOI: 10.37421/2168-9547.2025.14.517
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Brief Report Pages: 1 - 3

Molecular Foundations of Cellular Life: Mechanisms and Dynamics
Ricardo Sanchez*
DOI: 10.37421/2168-9547.2025.14.520
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Brief Report Pages: 1 - 2

Advancing Molecular Visualization and Understanding
Maria Ignatova*
DOI: 10.37421/2168-9547.2025.14.521
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Commentary Pages: 1 - 3

Molecular Insights: Advancing Biology and Therapeutics
Aidan Fitzgerald*
DOI: 10.37421/2168-9547.2025.14.522
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Molecular Atlasing: Mapping Life's Complexity and Function
Tatiana Kovalenko*
DOI: 10.37421/2168-9547.2025.14.523
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Opinion Pages: 1 - 3

Molecular Motion: The Engine of Life
Andrea Rojas*
DOI: 10.37421/2168-9547.2025.14.524
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Molecular Architectures and Dynamics of Cellular Life
Vera Laskova*
DOI: 10.37421/2168-9547.2025.14.525
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Molecular Biology's Cancer Breakthroughs: Precision Therapies
Emilio Garcia*
DOI: 10.37421/2168-9547.2025.14.526
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Molecular Cartography: Mapping Biology's Cellular Landscape
Lina Chen*
DOI: 10.37421/2168-9547.2025.14.527
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