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6757 Peer Reviewed Journals In Blood Cancer | Open Access Journals
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Advances in Robotics & Automation

ISSN: 2168-9695

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6757 Peer Reviewed Journals In Blood Cancer

Blood Cancer Journal seeks to publish articles of the highest quality related to hematologic malignancies and related disorders. The Journal will consider for publication original research, reviews, guidelines and letters that are considered to be of high impact in the field. Topics of particular interest include, but are not limited to, the following: Preclinical studies of new compounds, especially those that provide mechanistic insights Clinical trials and observations Reviews related to new drugs and current management of hematologic malignancies Novel observations related to new mutations, molecular pathways, and tumor genomics  Cancer arises owing to the combined effects of multiple somatic mutations, which are likely to be acquired at different times.  Early mutations may be present many years before disease develops. In some models of cancer development, early mutations lead to clonal expansions by stem cells or other progenitor cells. Such clonal expansions greatly increase the likelihood that later, cooperating mutations would arise in cells that already contain the earlier, initiating mutations. To understand the pathogenesis of proliferative diseases, it is important to know the extent to which clonal expansions occur and precede cancer.  Hematopoietic stem-cell population dynamics may precede many hematologic cancers, including myeloproliferative neoplasms, myelodysplastic syndromes, acute myeloid leukemia (AML), and chronic lymphocytic leukemia. For example, in some patients, stem cells carrying a subset of the mutations present in the cancer cells are able to survive chemotherapy; subsequently, these cells acquire novel mutations, triggering a relapse. This suggests that a clonally expanded stem-cell population may have existed before the cancer developed.

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Citations: 1275

Advances in Robotics & Automation received 1275 citations as per Google Scholar report

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