Nuclear Medicine & Radiation Therapy

ISSN: 2155-9619

Open Access

Current Issue

Volume 13, Issue 9 (2022)

    Case Report Pages: 1 - 3

    18F-FDG PET/CT Revealed of Rare Primary Lyphoepithelionma-Like Carcinoma of the Lung: A Case Report and Literature Review

    Xue Liu, Tao Jiang and Bao Zhang*

    DOI: 10.37421/2155-9619.2022.13.506

    We present a case of a 44-year-old woman was hospitalized for one year with intermittent coughing and expectoration. She has no history of smoking or previous medical conditions. DNA test positive for Epstein-Barr virus. Chest computed tomography (CT) showed a soft tissue mass in the left lower lobe of the lung and non-uniformity of image density. Part of the bronchus in the lower lobe of the left lung was compressed and occluded. On contrast-enhanced CT, the mass was inhomogeneously enhanced. Fluorine-18-fluorodeoxyglucose positron emission tomography/ CT (18F-FDG PET/CT) revealed the mass had significant uptake of FDG and maximum standard uptake value (SUVmax) was 10.7. The subsequent histopathologic examination confirmed the diagnosis of a primary lung lyphoepithelionma-like carcinoma (LELC). The patient was treated with chemotherapy.

    Volume 13, Issue 6 (2022)

      Mini Review Pages: 1 - 2

      Resistant Regulatory Results of Molecularly Selected Therapy and its Repurposed Applications in Cancer Immunotherapy

      Tiancheng Zhang*

      DOI: 10.37421/2155-9619.2022.13.495

      The quick development of hostile to growth specialists encapsulates a more profound comprehension of disease pathogenesis. Until this point, chemotherapy, designated treatment, and immunotherapy are three mainstays of the world view for malignant growth treatment. The outcome of safe designated spot inhibitors (ICIs) infers thatrestoration of insusceptibility can effectively control cancer development, attack, and metastasis. Be that as it may, just a small portion of patients benefit from ICI treatment, which turns the focus on creating safe restorative procedures to beat the issue of an unsuitable reaction. Sub-atomic designated specialists were intended to kill disease cells with oncogenic transformations or transcriptional targets. Intriguingly, amassing smidgens of proof exhibit the immunostimulatory or immunosuppressive limit of designated specialists. By ideals of the great whittling down rate and cost of new immunotherapy investigation, drug reusing might be a promising way to deal with finding mix techniques to further develop reaction to immunotherapy. For sure, numerous clinical preliminaries researching the security and viability of the blend of designated specialists and immunotherapy have been finished. Here, we survey and talk about the impacts of designated anticancer specialists on the cancer resistant microenvironment furthermore, investigate their potential reused utilization in disease immunotherapy.

      Mini Review Pages: 1 - 2

      Resistant-interfered Reactions of Microplanar Radiotherapy with Little Animal Illuminator

      Victoria Benefield*

      DOI: 10.37421/2155-9619.2022.13.494

      Spatially fractionated radiotherapy has been displayed to significantly affect the invulnerable framework that vary from customary radiotherapy (CRT). We looked at a few parts of the invulnerable reaction to CRT comparative with a model of spatially fractionated radiotherapy (RT), named microplanar radiotherapy (MRT). MRT conveys many grays of radiation in submillimeter radiates (top), isolated by non-transmitted volumes (valley). We have fostered a preclinical strategy to apply MRT by a business little creature irradiator. Utilizing a B16-F10 murine melanoma model, we originally assessed the in vitro and in vivo impact of MRT, which exhibited huge treatment prevalence relative over CRT. Strangely, we noticed irrelevant treatment reactions when MRT was applied to Rag−/− and CD8-drained mice. An immuno-histological examination showed that MRT enrolled cytotoxic lymphocytes (CD8), while stifling the quantity of administrative T cells (Tregs). Utilizing RT-qPCR, that's what we saw, contrasted with CRT, MRT, up to the portion that we applied, essentially expanded and didn't soak CXCL9 articulation, a cytokine that assumes a critical part in the fascination of enacted T cells. At long last, MRT joined with against CTLA-4 removed the growth in portion of the cases, and prompted delayed foundational antitumor resistance.

      Volume 13, Issue 7 (2022)

Google Scholar citation report
Citations: 636

Nuclear Medicine & Radiation Therapy received 636 citations as per Google Scholar report

Nuclear Medicine & Radiation Therapy peer review process verified at publons

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