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Neurological Disorders

ISSN: 2329-6895

Open Access

Current Issue

Volume 8, Issue 4 (2020)

    Research Article Pages: 1 - 4

    Acute Pain and Cognition in Older Persons

    Nour Alkaduhimi, Merve Yilmaza and Erik Johannes Anton Scherder

    DOI: 10.37421/J Neurol Disord.2020.8.423

    Objectives: So far studies have focused on the relationship between cognitive impairment and chronic pain perception in elderly. The present study examined the relationship between acute pain perception and cognition. Methods: Fifty-nine nursing home residents underwent a neuropsychological assessment aimed at cognition. Assessment of acute pain took place directly following a venipuncture, utilizing the Coloured Analogue Scale (CAS). Results: Acute pain perception showed a negative relationship with the scores on the cognitive tasks. Other variables such us hypertension and medication usage did not seem to influence the relationship. Discussion and Conclusion: The present findings imply that the more cognitive impairment a person experiences, the higher the acute pain experience is. This increases the risk for under treatment of pain.

    Research Article Pages: 1 - 4

    77 Cases of Treating Parkinson's Disease by Eaulier Systemic Current Treatment Method

    Cheung Chun Luke

    DOI: 10.37421/J Neurol Disord.2020.8.427

    Objective: To observe the curative effect of Eaulier systemic current treatment method on Parkinson's disease. Methods: The treatment of 77 patients with primary Parkinson's disease from September 2013 to December 2018 was treated with Eaulier systemic current treatment method, to observe the changes of symptoms and signs, such as quiescent tremor, rigidity, slow movement, abnormal posture and gait, facial expression, fine movement of hand, insomnia, constipation and so on. The curative effect was evaluated according to symptoms, signs and Webster scores. The data were processed by statistics, t-test was used for measuring data and X2-test was used for counting data. The difference was significant when P<0.05. Results: After treatment, the symptoms and signs of resting tremor, stiffness, and retardation of movement, abnormal posture and gait, rigid facial expression, inflexible fine movements of hands, insomnia and constipation were significantly improved. Among them, ADL level was significantly improved, with the levels of 70.65 ± 7.11 and 88.87 ± 8.67 before and after treatment, respectively (P< 0.01), and MMSE were 24.43 ± 1.42 and 25.56 ± 1.63 before and after treatment, respectively (P< 0.05). Wechsler's comprehensive assessment was 15.78 ± 2.76 and 8.47 ± 1.81 before and after treatment (P<0.01), and the Hamilton Depression Scale was 49.77 ± 5.37 and 48.96 ± 5.68 before and after treatment (P>0.05). The symptoms and signs of stiff countenance inflexibility of fine hand movements, insomnia and constipation were improved obviously. Conclusion: Eaulier systemic current treatment method has a good effect on Parkinson's disease with no side effects. The method is simple and feasible, and it is worth popularizing to application.

    Case Report Pages: 1 - 6

    Neuro-Behcet Disease-A Case Report and Review

    Mihael Tsalta-Mladenov, Darina Georgieva-Hristova and Silva Andonova

    DOI: 10.37421/J Neurol Disord.2020.8.425

    Behcet’s disease (BD) is a multisystem autoimmune relapsing vasculitis with almost unknown etiology, which involves both large and small vessels. In Neuro-Behcet’s disease (NBD), the CNS can be involved generally in two ways. The parenchymal type is caused by development of an immunemediated meningoencephalitis, which predominantly involves the brainstem and diencephalon region. Non-parenchymal type is a consequence of thrombosis within the dural venous sinuses. Peripheral nervous system generally preserved or involved in very rare cases. The diagnosis of NBD is based on the clinical presentation and the typical NBD lesions in brain magnetic resonance imaging (MRI). The development and disappearance of lesions at MRI correlate with the course of clinical neurologic deficits. Brain MRI in chronic NBD usually shows brain or brainstem atrophy and in some cases “black holes”. We present a case report of a female with NBD and a thoral review of this disease.

    Case Report Pages: 1 - 3

    Rapidly Progressive Dementia as a Manifestation of Relapse in Mantle Cell Lymphoma: Experience in Diagnosis and Treatment

    Julian Andres Gutierrez Gutierrez, Juan Pablo Duran and Miguel Arturo Silva Silva

    DOI: 10.37421/J Neurol Disord.2020.8.428

    Rapidly progressive dementia is an entity that has a multiple and heterogeneous etiology. It is characterized by the alteration of two or more cognitive domains in a period of less than 1 to 2 years. The involvement of the central nervous system attributed to mantle cell lymphoma is rare with a poor prognosis in the short term and mainly debuts in the late stages of the disease as a relapse. A 61-year-old male with a history of mantle cell lymphoma who presents a relapse of the central nervous system, given by a clinical course compatible with a rapidly progressive dementia and which is confirmed by flow cytometry studies in cerebrospinal fluid, which show a 53 , 8% of mature lymphoid population: CD45, CD19, CD20, HLA-DR, BCL2. It presents an adequate response to management with a tyrosine kinase inhibitor (Ibrutinib), resolving clinical symptoms and imaging findings.

    Editorial Pages: 1 - 1

    Editorial Note for Journal of Neurological Disorders

    Hiroshi Nakanishi

    DOI: 10.37421/J Neurol Disord.2020.8.426

    As our readers know, Journal of Neurological Disorders is the most preferred and highly accessed Journal in the field of Neurological Disorders. The Journal is indexed in Index Copernicus, Open J Gate, Academic Keys among many other reputed scientific databases. At many instances members of the editorial board also prefer to submit their articles. Such practice is common in other reputed specialty Journals. In fact, JND encourages editorial board members to actively contribute. However, no special privileges are given to anyone. All scientific manuscripts including editorials are subjected to peer review. We ensure that the peer-review process is fair, unbiased (single blind review system-where reviewer recognizes author but author does not recognize reviewer) and timely. We express our sincere gratitude to all our reviewers for their long standing support, their effort and time in evaluating the manuscripts. The peer-review process converts the preliminary manuscript submission into a citable standard publication.

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