Opioid Use Disorder (OUD) may be a substance use disorder concerning the utilization of an opioid. Any such disorder causes significant impairment or distress. Signs of the disorder include a robust desire to use opioids, increased tolerance to opioids, difficulty fulfilling obligations, trouble reducing use, and withdrawal symptoms with discontinuation. Opioid withdrawal symptoms may include nausea, muscle aches, diarrhea, trouble sleeping, agitation, and a coffee mood. Addiction and dependence are components of a substance use disorder. Complications may include opioid overdose, suicide, HIV/AIDS, hepatitis C, and problems at college, work, or home. Opioids include substances like heroin, morphine, fentanyl, codeine, dihydrocodeine, oxycodone, and hydrocodone. Within the us, a majority of heroin users begin by using prescription opioids, which will even be bought illegally. Risk factors for misuse include a history of substance use, substance use among family and friends, mental disease , low socioeconomic status, and race.