DOI: 10.37421/2329-9126.2023.11.526
Chenge Criel*
Chronic illness is a term used to describe any long-term health condition that persists over time and often requires ongoing treatment. Examples of chronic illnesses include diabetes, arthritis, cardiovascular disease, chronic pain conditions, and autoimmune diseases, among others. While the physical toll of these conditions is widely recognized, the mental health implications are often underestimated. The reality, however, is that chronic illness can significantly affect mental health in ways that may not always be immediately apparent to the individual or their caregivers. The relationship between chronic illness and mental health is complex and bidirectional, meaning that chronic illness can lead to mental health challenges, and mental health challenges can, in turn, exacerbate the physical symptoms of illness.
Eva Pawlas*
First responders are the first individuals to arrive at the scene of an emergency, and their role is crucial in providing initial care and stabilizing patients before they are transported to more advanced medical facilities. These professionals include Emergency Medical Technicians (EMTs), paramedics, fire-fighters, and police officers. Each plays an essential role in emergency care, working together as a team to mitigate the effects of medical crises, accidents, natural disasters, and other unexpected events. The importance of their training, decision-making abilities, and ability to work under pressure cannot be overstated, as their actions in the initial moments of an emergency can significantly impact the outcome of a patient's recovery.
Friedman Carlos*
Living with chronic pain is a daily challenge that millions of people face across the world. Unlike the temporary discomfort that most people experience from time to time, chronic pain is persistent, lasting for months or even years. It can be the result of a variety of conditions, ranging from arthritis and fibromyalgia to back problems or nerve damage. But regardless of the cause, the impact on one's daily life is profound. Navigating daily life with chronic pain involves not just managing the physical discomfort, but also contending with the emotional and psychological toll it takes. Over time, chronic pain can change the way people live, how they see themselves, and how they relate to others. The journey is complex, with challenges that ebb and flow, and strategies that must be adjusted as time goes on.
Balzer Barbel*
Knowing when to see a General Practitioner (GP) can be a confusing decision for many people. It's easy to feel unsure about whether your symptoms are serious enough to warrant a doctor's visit or if it's something that will resolve on its own. A significant number of individuals delay seeing a GP, thinking they can manage their symptoms themselves, but in some cases, delaying medical care can lead to complications or worsen the problem. On the other hand, visiting a doctor unnecessarily can lead to wasted time and resources. Striking the right balance is key. Understanding when to seek medical attention can prevent small issues from becoming serious and provide you with the guidance necessary for maintaining your health.
Jawad Meier*
The role of physicians in healthcare has long been rooted in the foundational principles of medical practice diagnosis, treatment, and care. However, over the years, the role of physicians has undergone a significant transformation. This evolution is due to multiple factors such as advances in medical technology, changes in healthcare delivery systems, the expansion of patient expectations, and the globalized nature of healthcare information. While physicians have always been at the forefront of patient care, the modern healthcare landscape has placed new demands on their expertise, responsibilities, and approaches to patient care. In the past, physicians were seen as the undisputed authorities when it came to patient care. Their judgment was central to all medical decisions, and patients often adhered to their advice without question.
Meena Alin*
Sleep is one of the most important yet often overlooked processes that our body undergoes on a daily basis. While it might seem like a passive activity, sleep is crucial to maintaining our physical and mental health. It is during sleep that our body undergoes a series of restorative processes that are essential for survival and well-being. Despite its importance, the true understanding of sleep's physiology and its profound effects on the body remains a subject of scientific exploration. Yet, the basic principle is simple: sleep is not merely a break from the demands of life but a vital period during which the body recharges, repairs, and performs essential functions to maintain health. The human body requires sleep for many reasons, ranging from cognitive functioning to physical restoration.
Star Saukanj*
Physiology is the branch of biology that studies the functions and mechanisms occurring within living organisms. It focuses on how biological systems work at molecular, cellular, tissue and organ levels to maintain life. By examining the normal functioning of the body, physiology also provides invaluable insights into how these functions can be disrupted, leading to disease. In both health and disease, understanding physiology is crucial as it informs medical practice, disease prevention, and therapeutic strategies. The body’s physiological processes are essential for maintaining homeostasis, which is the stable internal environment necessary for proper functioning. Homeostasis regulates factors such as body temperature, pH, blood pressure, and glucose levels. When these processes become unbalanced or disrupted, the body is prone to disease.
Karim Rahman*
Primary Health Organizations (PHOs) play a crucial role in the healthcare system, serving as the cornerstone of accessible and comprehensive health services. These organizations, operating at the community level, aim to provide primary care that is continuous, comprehensive, and coordinated. They bridge gaps in healthcare delivery by focusing on prevention, early diagnosis, treatment, and long-term management of chronic conditions, often in collaboration with specialists, hospitals, and public health agencies. The primary objective of PHOs is to improve the overall health of populations, reduce the burden on secondary and tertiary healthcare systems, and enhance the patient experience by offering services that are closer to where people live and work.
Stephen Kellett1,2*, Melanie Simmonds-Buckley1,2, Mike Seneviratne1, Katherine Morgan2, Mark Boon3 and Ian Seymour4
Objective: The accurate prescription of antidepressants is technically complex and difficult to achieve. This project therefore sought to evaluate the feasibility of integrating an evidence-based decision support tool (Predictix) into General Practice. Methods: This was a real-world mixed methods evaluation in N=2 General Practices of the experiences of patients (n=24), General Practitioners (GPs; n=4) and Predictix administrators (n=2). Suitable patients were assessed using Predictix and this produced a recommendation for the likely most efficacious anti-depressant. Two patient study groups were created (a) antidepressant recommended by Predictix and (b) a GP clinical opinion override group. Both groups of patients were followed up at 12-weeks. The PHQ-9 was embedded in the Predictix assessment, and the measure was recompleted at 12-weeks follow-up. Qualitative interviews were conducted with GPs, patients and administrators and a reflexive thematic analysis (RTA) conducted. Results: It took 20-minutes to administer Predictix and then 3-days for the prescription to be issued. N=19 (88%) received a Predictix selected antidepressant (2 participants dropped out during the Predictix assessment), of whom 8/19 recovered. The N=3 (14%) in the GP override group all recovered. The common qualitative themes across GPs, patients and administrators were managing expectations, individualized care and burden. Conclusion: Whilst decision support tools have the potential for increasing prescribing accuracy for antidepressants, practical and psychological barriers to implementation need to be identified and resolved.
Techane Sisay Tuji and Addisu Dabi Wake
The infant young child feeding model of World Health Organization (WHO) suggests introducing complementary food for new born babies starting at the sixth month. Breast milk has to be round out by any other foods to fill the nutrient demand of the child. These complementary foods are required to fill the calorie, protein, and micronutrient gap between the total nutritional need of the child and the amount contributed by the breast milk. Sufficient complementary food has to be diversified and prepared from different food groups in a solid or semisolid form and needs to be commenced timely from the sixth month of the child’s age by implementing the quality of foods consumed as the child get older.
Tuji Techane Sisay* and Addisu Dabi Wake
Background: Accurate complementary feeding plays a great role in preventing childhood under nutrition, infectious disease, and mortalities. The available data suggests that the rates for Minimum Acceptable Diet (MAD) are low across all regions worldwide. For instance, rates are four in every ten (41.1%), in East Asia and Pacific and lowest in West and Central Africa at 8.6%, East and South Africa at 9.8%, and South Asia at 13.0%. However, Factors Associated towards Mothers Practicing Acceptable Diet of 6–23 Months Old Children living in study area is unknown. Therefore, this study was aimed to assess factors associated towards mothers practicing acceptable diet of 6-23 months old children in Gimbichu Woreda, Oromia Regional State, Ethiopia.
Materials and methods: A community-based cross-sectional study was conducted among 782 mothers/caregivers paired with infants and children aged 6 to 23 months with a response rate of 97.1%, from March 12 to April 08, 2019. One-stage cluster sampling technique was employed. A structured pretested tool was used to collect the data. The binary logistic regression analysis was applied for MAD. All variables were transformed to multivariable logistic regression model irrespective of any transforming criteria to control the effects of confounder/s and to identify statistically significant variables. Finally, the variables which had independent correlations with MAD were identified on the basis of Adjusted Odds Ratio (AOR) and a p-value less than 0.05with 95%CI were claimed as statistically significant.
Results: The proportion of acceptable diet was 30.1% (26.7, 33.1%). Mothers’ secondary and above educational level (AOR= 2.78, 95%CI (1.12, 6.89), mothers attending PNC (AOR=6.45, 95%CI (1.71, 13.33), mothers’ who had good knowledge in infant feeding AOR=8.46, 95%CI; (3.81,11.80), mothers’ involvement on feeding AOR=5.10, 95%CI; (2.47,10.52), mothers whose attending ANC (AOR=3.86, 95% CI (1.99,14.94), wealth index ranked at richest category (AOR=3.24 ,95%CI (1.24,8.45) and husbands’ involvement (AOR=5.75, 95% CI (1.18,12.79) were positively associated with MAD.
Conclusion: The proportion of MAD practice by infants and children of the study area was low. Mothers’ secondary and above educational level, mothers’ attending PNC, mothers’ who had good knowledge on infant feeding, mothers’ involvement on feeding, mothers whose attending ANC, wealth index and husband’s involvement were factors positively associated with MAD. Assuring mother’s involvement on decision making and promoting husband involvement on infant and child feeding are strongly recommended to mitigate the problem.
Telksew Yelma Yezengaw*, Tariku Dingeta Amante, Tesfaye Assebe Yadeta and Biruk Shalmeno Tusa
Background: Stillbirth rate is an important indicator of access to quality antenatal and delivery care services. Many previous pocket studies were conducted to assess the magnitude of stillbirth and its association with premature rupture of membrane. However, the level of stillbirth, as well as its relationship with Premature Rupture of Membrane (PROM) varies from study to study. Objectives: This systematic review and meta-analysis was conducted to estimate the pooled prevalence of stillbirth and its association with the early rupture of membranes in sub-Saharan Africa. Search strategy: Electronic databases such as PubMed Central PMC, Cochrane library, Medline via Virtual Health Library (VHL), HINARI (Health Inter Network Access to Research Initiative) portal, and Google scholar were used for searching for original articles. Selection criteria: All Published and unpublished observational studies (prospective and retrospective cohort studies, case-control studies, and cross-sectional studies) that deal with stillbirth and their association with early rupture of membranes in sub-Saharan African women were included. Data collection and analysis: The extracted data analyses were done using STATA (version.16.0) software. Texts, figures, and tables were used to describe the included original articles. The heterogeneity of the studies was checked by I-squared statistics. A Random-effects method was applied to estimate the pooled prevalence of stillbirth and the effect size of the early rupture of membranes in sub-Saharan Africa. Subgroup analysis was performed based on region (East, West, Central, and Southern Africa) and year of study (before 2015 and after 2015). A funnel plot and Egger’s regression test was used to see publication bias. Main result: Pooled prevalence of stillbirth in sub-Saharan Africa was 6.4% (95% CI: 5.5-7.3). In sub-group analysis, Southern African regions had a higher stillbirth prevalence and the western African regions had a lower than East and Southern Africa. The prevalence of stillbirth in the region is increased from 4.1% (95% CI: 2.2–6.0) before 2015 to 7.1%(95% CI: 5.8-8.3) after 2015. The pooled odds ratio results from seven studies showed the non-significant effect of early rupture of membrane on stillbirth (pooled OR=1.54, 95% CI: 0.26-2.82). According to the regression test (Egger test), there was no small study effects or publication bias (P=0.108). Conclusions: The pooled prevalence of stillbirth in sub-Saharan Africa was relativity high. The analysis establishes the minimal effects of early rupture of membrane on stillbirth. Therefore, we recommend that strengthening the testing intervention is crucial to reduce the still relatively high stillbirths. Funding: No fund was received for this work.
H. Innesu
Prognosis is the identity of the character and reason of a sure
phenomenon. Analysis is used in lots of exclusive disciplines, with
versions in the use of good judgment, analytics, and revel in, to
determine "motive and impact". In systems engineering and computer
science, it's far usually used to determine the reasons of symptoms,
mitigations, and answers. Analysis is frequently tough, because many
signs and symptoms and symptoms are nonspecific, and can best be
undertaken with the aid of registered and licensed health experts. As
an instance, redness of the skin (erythema), through itself, is an
indication of many disorders and for this reason does not tell the
healthcare expert what is incorrect. Accordingly differential analysis,
wherein several feasible reasons are compared and contrasted, need
to be achieved. This entails the correlation of numerous pieces of
records observed by using the popularity and differentiation of
patterns. Occasionally the procedure is made clean by a sign or
symptom (or a set of several) this is pathognomonic. The method of
differential analysis is based totally on locating as many candidate
illnesses or situations as viable which can in all likelihood purpose
the symptoms or symptoms, observed via a process of removal or as
a minimum of rendering the entries greater or much less likely by
means of similarly medical assessments and other processing,
aiming to attain the point wherein handiest one candidate disorder or
condition stays as likely. The final end result may additionally remain
a list of feasible conditions, ranked so as of possibility or severity.
One of these lists is frequently generated by means of computeraided
analysis systems. In a pattern reputation approach the
company makes use of experience to apprehend a sample of
scientific characteristics. Its miles specifically primarily based on sure
symptoms or signs being related to certain diseases or situations,
now not necessarily related to the extra cognitive processing
concerned in a differential analysis. This will be the number one
method utilized in cases where illnesses are "apparent", or the
issuer's revel in may additionally allow her or him to understand the
circumstance quick. Theoretically, a certain pattern of symptoms or
signs and symptoms can be at once associated with a sure therapy,
even without an exact decision concerning what's the actual disease,
but this type of compromise contains a full-size hazard of missing a
analysis which simply has a distinctive therapy so it can be
restrained to instances wherein no diagnosis may be made. Over
diagnosis is the diagnosis of "ailment" so one can by no means
purpose signs and symptoms or loss of life at some stage in a
affected person's lifetime. It’s far a problem as it turns people into
patients unnecessarily and due to the fact it could cause monetary
waste (overutilization) and remedies which could reason harm. Over
diagnosis takes place whilst a disorder is diagnosed effectively, but
the analysis is inappropriate. A correct prognosis can be beside the
point because treatment for the sickness is not to be had, now not
needed, or now not desired. Clinical diagnosis or the actual
procedure of creating a analysis is a cognitive manner. A clinician
uses several assets of information and puts the portions of the puzzle
together to make a diagnostic impression. The preliminary diagnostic
affect can be a broad time period describing a category of sicknesses
in place of a selected ailment or circumstance. After the initial
diagnostic influence, the clinician obtains comply with up
assessments and processes to get extra facts to assist or reject the
authentic prognosis and could try to narrow it all the way down to an
extra unique stage. Diagnostic strategies are the specific tools that
the clinicians use to slender the diagnostic opportunities.
Bingxi Zhao
Anesthesiology is the medical uniqueness involved with the overall
perioperative care of patients earlier than, throughout and after
surgery. It encompasses anesthesia, intensive care medicine,
important emergency medicinal drug, and pain medicinal drug. A
medical doctor specialized in anesthesiology is known as an
anesthesiologist. There are special approaches of referring to the
sector of anesthesiology and physicians who specialize in it relying
on the area of the world. As a strong point, the core element of
anesthesiology is the exercise of anesthesia. This comprises using
diverse injected and inhaled medications to provide a loss of
sensation in patients, making it feasible to carry out approaches that
might in any other case motive intolerable ache or be technically
unfeasible. Safe anesthesia calls for in-depth understanding of
diverse invasive and non-invasive organ aid techniques which might
be used to control sufferers' critical capabilities while under the
results of anesthetic pills; those include superior airway management,
invasive and non-invasive hemodynamic video display units, and
diagnostic strategies like ultrasonography and echocardiography.
Anesthesiologists are predicted to have professional knowledge of
human physiology, medical physics, and pharmacology, as well as a
large general understanding of all regions of medication and surgical
procedure in every age of patients, with a particular cognizance on
the ones components which might also effect on a surgery. In latest
decades, the function of anesthesiologists has broadened to attention
now not just on administering anesthetics all through the surgical
operation itself, however additionally ahead so as to pick out highrisk
patients and optimize their fitness, in the course of the process to
keep situational awareness of the surgical procedure itself to be able
to improve protection, in addition to afterwards so as to sell and
enhance healing. This has been termed "perioperative medicine". In
the 19th century, the beginnings of preferred anesthesia began with
the advent of ether in Boston and chloroform inside the UK to bring
about a state of unawareness and unresponsiveness to the ache of
surgical insult. With the isolation of cocaine in the mid-nineteenth
century there started out to be tablets available for neighborhood
anesthesia. Through the stop of the nineteenth century, the quantity
of pharmacological alternatives multiplied and that they commenced
to be implemented both peripherally and neuraxially. Then within the
20th century neuromuscular blockade allowed the anesthesiologist to
completely paralyze the affected person pharmacologically and
breathe for him or her through mechanical air flow. With those new
tools, the anesthetist may want to intensively manage the affected
person's body structure bringing about vital care remedy, which, in
many nations, is in detail related to anesthesiology. Anesthesiologists
have key roles in primary trauma, resuscitation, airway management,
and worrying for other patients outside the operating theatre who
have critical emergencies that pose an instantaneous danger to
existence, again reflecting transferable competencies from the
operating room, and allowing continuity of care whilst patients are
brought for surgical operation or in depth care. This branch of
anesthesiology is together termed critical emergency remedy, and
includes provision of pre-medical institution emergency medication
as a part of air ambulance or emergency scientific offerings, as well
as safe switch of significantly ill sufferers from one part of a clinic to
another, or among healthcare facilities. Anesthesiologists typically
shape part of cardiac arrest groups and speedy reaction teams
composed of senior clinicians that are without delay summoned while
a affected person's coronary heart stops beating, or after they
deteriorate acutely whilst in sanatorium. Exclusive models for
emergency medicine exist internationally: inside the Anglo-American
version, the patient is hastily transported by means of non-health
practitioner vendors to definitive care along with an emergency
department in a health center. Conversely, the Franco-German
technique has a health practitioner, often an anesthesiologist, come
to the patient and offer stabilizing care inside the area. The patient is
then triaged at once to the appropriate branch of a health facility.
Lei Wang
Neuroscience is the medical study of the apprehensive machine.
It’s far a multidisciplinary technological know-how that combines
physiology, anatomy, molecular biology, developmental biology,
cytology, pc technology and mathematical modeling to apprehend the
fundamental and emergent residences of neurons, glia and neural
circuits. The expertise of the biological basis of gaining knowledge of,
reminiscence, conduct, belief, and attention has been defined by
using Eric Kandel because the "remaining assignment" of the
biological sciences. The view that the heart became the supply of
awareness becomes no longer challenged till the time of the Greek
physician Hippocrates. He believed that the mind turned into now not
simplest concerned with sensation—due to the fact that most
specialized organs (e.g., eyes, ears, tongue) are located in the head
close to the mind—however becomes also the seat of intelligence.
Plato additionally speculated that the mind become the seat of the
rational a part of the soul. Aristotle, but, believed the coronary heart
become the middle of intelligence and that the mind regulated the
quantity of warmth from the coronary heart. This view became
normally normal until the Roman health practitioner Galen, a follower
of Hippocrates and doctor to Roman gladiators, determined that his
sufferers misplaced their mental faculties after they had sustained
harm to their brains. In parallel with these studies, paintings with
brain-damaged sufferers by Paul Broca cautioned that positive
regions of the mind had been answerable for certain functions. On
the time, Broca's findings had been visible as a affirmation of Franz
Joseph Gall's idea that language turned into localized and that sure
mental functions have been localized in unique areas of the cerebral
cortex. The localization of function hypothesis became supported via
observations of epileptic patients performed by way of John Hugh
lings Jackson, who effectively inferred the organization of the motor
cortex by looking the progression of seizures via the frame. Carl
Wernicke further advanced the concept of the specialization of
particular brain systems in language comprehension and production.
present day studies through neuroimaging techniques, still makes
use of the Bradman cerebral cytoarchitectonic map (relating to study
of cell structure) anatomical definitions from this period in continuing
to show that distinct areas of the cortex are activated inside the
execution of unique obligations. The medical take a look at of the
anxious machine extended considerably for the duration of the
second one half of the 20 th century, basically due to advances in
molecular biology, electrophysiology, and computational
neuroscience. This has allowed neuroscientists to have a look at the
anxious gadget in all its factors: how it's far structured, the way it
works, how it develops, the way it malfunctions, and how it could be
modified. Neuroscience is also allied with the social and behavioral
sciences, as well as with nascent interdisciplinary fields. Examples of
such alliances encompass neuroeconomics, choice theory, social
neuroscience, and neuromarketing to address complex questions
about interactions of the brain with its environment. A observe into
purchaser responses for instance uses EEG to research neural
correlates related to narrative transportation into testimonies
approximately strength performance. As an example, it has emerged
as viable to apprehend, in a good deal detail, the complicated
strategies occurring within a single neuron. Neurons are cells
specialized for conversation. They’re capable of talk with neurons and
other mobile kinds through specialized junctions called synapses, at
which electrical or electrochemical indicators can be transmitted from
one mobile to some other. Many neurons extrude an extended skinny
filament of axoplasm known as an axon, which may expand to distant
parts of the body and are able to swiftly wearing electric alerts,
influencing the activity of other neurons, muscle tissues, or glands at
their termination points. An anxious device emerges from the
assemblage of neurons which might be connected to each other.
Journal of General Practice received 1047 citations as per Google Scholar report
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