Journal of Dermatology and Dermatologic Diseases

Shital Poojary

Publications

• Review Article
  Genetics of Vitiligo: An Insight
  Author(s): Shital PoojaryShital Poojary
  
  Vitiligo is the most common depigmenting disorder having a major impact on the quality of life of patients. Despite continued progress toward an elucidation of the biochemical, genetic and immunopathological pathways in vitiligo, a definitive cure remains elusive. During the past few decades, advances in the field of molecular genetics have enriched us in understanding the etiopathogenesis of vitiligo. Several candidate genes have been associated with susceptibility to vitiligo. They include genes important for melanin biosynthesis, response to oxidative stress and/or regulation of autoimmunity. A recent genome-wide scan performed on families with numerous members presenting with vitiligo has clearly revealed linkage of susceptibility loci especially autoimmune susceptibility loci. Genetic studies have helped us identify not only the natural course and clinical aspects of vitiligo but.. Read More»
  DOI: 10.4172/2376-0427.1000178

  Abstract PDF