Journal of Dermatology and Dermatologic Diseases

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Volume 7, Issue 1 (2020)

Case Report Pages: 1 - 3

Recurrent Attack of Metformin Induced Bullous Pemphigoid
Pravalika Lashkar*, Pavani Thota, Ravi Chander Thatipelli and Shalini Reddy Polepalli
DOI: 10.37421/JPD.2020.7.284
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Bullous Pemphigoid is the large fluid filled blistering rare skin disease. This occurs when our immune system attacks the thin layer of inner tissue of outer layer of skin. Exact reason for the abnormal immune response is unknown, but this can be triggered by certain drugs like Phenacetin, Captopril, Ibuprofen, Penicillamine, etc. A 42 years old male patient of known diabetic mellitus joined in inpatient department of the hospital with chief complaints of itching, fluid filled blisters since 1 week over chest and lower limbs and scalp and gradually progressed to upper limb and face. On examination of past history, two months back he admitted in hospital with same complaints. He was treated with Corticosteroids, anti-histamine, vitamin supplement and antibiotics. Metformin is widely used as first line agent for treatment of type-2 diabetes mellitus. Drug induced Bullous Pemphigoid has been associated with many drugs, but Metformin is not one among them. Here we a report a case on Metformin induced recurrent attack of Bullous Pemphigoid.
Case Report Pages: 1 - 3


Atypical Localization of a Diffuse Primary Cutaneous B Lymphoma with Large Cells of Leg Type

Selma Benkirane*, Sara Elloudi, Mounia Bennani, Hanane BayBay and Fatima Zahra Mernissi

DOI: 10.37421/JPD.2020.7.283

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Cutaneous B-cell lymphomas are a malignant proliferation of lymphocytes of the B-cell type. Mutation occurring at different points in B cell development leads to different forms of lymphoma. Rarely, it presents as verrucous plaques or widespread garland-like lesions. They are typically red to bluish. They are mainly found on one or both legs but it affects other sites in 10–15%. It represents an aggressive subtype of PCBCL. Primary cutaneous diffuse large B-cell lymphomas of leg type are rare, occur mainly in very old women, preferentially localize in the lower limbs and in 10 to 15% of cases, they are localized in another part from the body. We describe a case in a 66 year old man with an atypical localization in the left shoulder.