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Journal of Dermatology and Dermatologic Diseases

ISSN: 2684-4281

Open Access

Melanosis Coli

Melanosis coli, also pseudomelanosis coli, is a disorder of pigmentation of the wall of the colon, often identified at the time of colonoscopy. It is benign, and may have no significant correlation with disease. The brown pigment is lipofuscin in macrophages, not melanin. The most common cause of melanosis coli is the extended use of laxatives, and commonly anthraquinone containing laxatives such as Senna, Aloe Vera and other plant glycosides.

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