Transplantation Technologies & Research

Sebastian Schubl

Publications

• Review Article
  Induction Therapy: A Modern Review of Kidney Transplantation Agents
  Author(s): Cheguevara Afaneh, Meredith J Aull, Sebastian Schubl, David B Leeser and Sandip KapurCheguevara Afaneh, Meredith J Aull, Sebastian Schubl, David B Leeser and Sandip Kapur
  
  Kidney transplantation remains the most effective modality for the treatment of end-stage renal disease. The development of induction therapy has significantly reduced the incidence of acute rejection within the first six months following kidney transplantation. As a result, induction therapy is typically administered in the majority of kidney transplants. Moreover, early graft function has also improved with the advent and routine administration of induction therapy. Effective induction therapy has also expanded the donor pool as it allows for more effective utilization of marginal donor kidneys including expanded criteria donors and donors after cardiac death. It may also benefit higher immunologic risk recipients such as highly sensitized, African American, and repeat transplant patients. Poly- and monoclonal antibody agents are available for use as induction agents, including rabb.. Read More»
  DOI: 10.4172/2161-0991.S4-001

  Abstract PDF