Molecular Biology: Open Access

ISSN: 2168-9547

Open Access

Prashant AP

Program Manager, Clinical Research, RLS,
Navi Mumbai

  • Review Article
    Global Challenges in Cardiovascular Drug Discovery and Clinical Trials
    Author(s): Prashant APPrashant AP

    Despite major advancement in drug development heart disease and stroke remain major public concern due to primary cause of death. In developing nations, more than 20-25 million peoples are projected to die due to cardiovascular disease by 2020. The burden of cardiovascular disease clearly remains both a major public health concern and growing global challenge. The number of cardiovascular drugs in the research pipeline has declined across all phases of development in the last 20 years even as cardiovascular disease has become the No. 1 cause of death worldwide. The reason for this trend is multifactorial but primary reason is cost of conducting cardiovascular outcome trials in the current regulatory environment that demands a direct assessment of risks and benefits. It is difficult to prove treatment benefits in cardiovascular space compared with other therapeutic areas like N.. Read More»
    DOI: 10.4172/2168-9547.1000193

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