Molecular Biology: Open Access

Neelamraju Sarla

Publications

• Research Article
  Distribution and Associations of GATA Repeats in Rice Genome
  Author(s): Adari Prasad Babu, K Aruna Kumari and Neelamraju SarlaAdari Prasad Babu, K Aruna Kumari and Neelamraju Sarla
  
  GATA repeats are associated with sex differentiation in man, buffalo, mouse and even in plants such as papaya. Human X-chromosome region Xp22 that escapes inactivation is ten-fold enriched in GATA repeats suggesting a role in preventing heterochromatinization. The close proximity of GATA repeats to matrix-associated regions (MARs) indicates a role in chromatin organization and function. Chromosome-wise distribution and density of GATA repeats, neighboring genes and Matrix associated regions were analyzed in rice. (GATA)3 and higher repeats were distributed non-randomly with the highest frequency on chromosome 11. About 60% of the repeats were found in intergenic regions flanked by regulatory genes involved in stress response or transposable elements. The GATA associated MAR sequences in rice had at least one or more of the consensus sequence to which GATA factors bind. The genomic mil.. Read More»
  DOI: 10.4172/2168-9547.1000173

  Abstract PDF