Transplantation Technologies & Research

Mohamed SA Mohamed

Publications

• Short Communication
  A New Strategy and System for the Ex Vivo Ovary Perfusion and Cryopreservation
  Author(s): Mohamed SA MohamedMohamed SA Mohamed
  
  Childern and young adults, who suffer from cancer, receive gonadotoxic therapy, which destroys their fertile abilities after survival. Ovarian cryopreservation and transplantation provides the promising solution to this problem, where the ovary can be removed before the gonadotoxic therapy and reimplanted after patient's survival, where the ovary is to be cryopreserved during the period of the therapy. However, cryopreservation of the whole ovary is still facing great obstacles, namely the ischemic reperfusion injury and the defective cryopreservation related to the defective ability to universally deliver the cryopreservation/warming solutions through the ovarian vascular bed. Meanwhile, the currently applied technique of ovarian tissue cryopreservation provides limited follicular recovery because many follicles are lost until the development of revascularization post-transplantation.. Read More»
  DOI: 10.4172/2161-0991.1000172

  Abstract PDF