Molecular Biology: Open Access

ISSN: 2168-9547

Open Access

Doris Henne-Bruns


  • Review Article
    Current Role of Molecular Genetics in Pediatric Surgery
    Author(s): Alexandre Serra and Doris Henne-BrunsAlexandre Serra and Doris Henne-Bruns

    Background: Molecular genetic techniques have greatly improved the understanding of pediatric illnesses. Based on our own experience, the aim of this review is to illustrate the importance of such molecular studies for the development of the pediatric surgery. Methods: Various molecular techniques for the investigation of DNA, RNA, Chromosomes, gene sequences, genomic rearrangements and gene amplifications have been employed to answer the clinical and therapeutic questions. Suitable statistic methods allowed the comparison of the results between patients and controls whenever possible. Results: We demonstrated that essential information for diagnostics and therapy of pediatric illnesses can be obtained through molecular genetic testing, including (but not limited to) translocations and consequent protein chimera expres.. Read More»
    DOI: 10.4172/2168-9547.1000133

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