Journal of Dermatology and Dermatologic Diseases

Anjali Jinghan

Publications

• Research Article
  Double Blind Placebo Controlled Trial to Evaluate of the Effectiveness of a Dietary Supplement Rich in Carotenoids as Adjunct to Topical Lightening Cream for the Treatment of Melasma: A Pilot Study
  Author(s): Wan Lin Teo, Emily Gan, Anjali Jinghan, Sai Yee Chuah, Khaiat Alain, Chee-Leok Goh and Steven ThngWan Lin Teo, Emily Gan, Anjali Jinghan, Sai Yee Chuah, Khaiat Alain, Chee-Leok Goh and Steven Thng
  
  Objectives: To evaluate the efficacy of an oral supplement containing carotenoids as an adjunct to a topical cosmetic lightening cream for the treatment of melasma. Methods: 44 subjects with melasma were recruited into a double-blinded, randomized, placebo controlled trial over 84 days at the Singapore National Skin Centre, to receive either an oral dietary supplement containing carotenoids or a placebo. All were prescribed a commercially available cream. Patients were assessed at onset, day 54 and day 84 by the Modified Melasma area and Severity Index (mMASI), photographic documentation, melanin and erythema indexes using a Mexameter®. Results: 44 patients completed the study. The median mMASI score fell significantly in both groups (both p<0.001). There was a greater decrease seen in those who received the.. Read More»
  DOI: 10.4172/2376-0427.1000164

  Abstract PDF