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Prader Willi Syndrome Impact Factor | Open Access Journals
Human Genetics & Embryology

Human Genetics & Embryology

ISSN: 2161-0436

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Prader Willi Syndrome Impact Factor

Prader – Willi syndrome (PWS) is a genetic disorder caused by the loss of function of specific genes. Symptoms in newborns include weak muscles, poor feeding, and slow growth. Beginning in childhood, the person becomes ever hungry, often leading to obesity and type 2 diabetes. Also, mild to moderate intellectual impairment and behavioral problems are typical. Those affected often have a narrow forehead, small hands and feet, short height, light skin and hair, and cannot have children. Approximately 74 percent of cases occur when part of the father's 15th chromosome is removed. The person has two copies of chromosome 15 from their mother and none from their father in another 25 per cent of cases.

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