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Postoperative Coagulopathy | Open Access Journals
Transplantation Technologies & Research

Transplantation Technologies & Research

ISSN: 2161-0991

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Postoperative Coagulopathy

Early and increased amounts of plasma have been associated with improved survival after penetration and blunt injury. However, no study involving burn patients has demonstrated the effects of intraoperative plasma administration on postoperative resuscitation needs. This study examined perioperative transfusion ratios [plasma: RBC (P: R)] and the role of early and aggressive plasma administration in a contemporary burn center. Avoiding plasma transfusion until a full volume of red blood cells has been replaced is not the only recommendation that has been disputed. There are many articles from military and civilian medical centers that find the 1: 3 plasma / RBC transfusion ratio insufficient. A retrospective study of patients in a combat support hospital found that a red blood cell transfusion rate of approximately 1: 1 resulted in an increased survival rate. While burn patients may not have an initial hemorrhage (although many of our military patients have other injuries that cause immediate hemorrhage), all patients who require large-scale excision and skin grafting may become candidates for blood transfusions. Given that our estimated average blood loss for this study was almost 1.5 L, it is not surprising that almost all of our severely burned patients ultimately require a transfusion. Christopher V Maani, Intraoperative plasma: the Rbc ratio affects the requirements of postoperative coagulopathy and resuscitation

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