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International Journal of Public Health and Safety

International Journal of Public Health and Safety

ISSN: 2736-6189

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Omega 6 Fatty Acids

Effective medical treatments for infertile men with idiopathic oligoasthenoteratospermia (OAT) have yet to be determined. This study considered two main objectives: (i) to measure changes in sperm parameters, omega-3 fatty acid (AF) composition and antioxidant activity; (ii) to determine if the administration of omega-3 AF affects sperm quality in infertile men with OAT. Two hundred and thirty-eight infertile men with idiopathic OAT were randomized to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), 1.84 g per day (EPAX 5500TG; Lysaker, Norway) or placebo for 32 weeks. The semen parameters were assessed according to WHO criteria and the concentrations of EPA and DHA were determined in red blood cells (red blood cells), seminal plasma and sperm at baseline and during a treatment period. 32 weeks. Among the randomized subjects, 211 (88.7%) completed the full 32-week randomization period. The antioxidant status of seminal plasma was also assessed by measuring superoxide dismutase (SOD) and catalase activity. In the total group of participants, all levels of EPA and DHA in red blood cells and seminal plasma were statistically significantly correlated with those in sperm (both P = 0.001). In seminal plasma, SOD-like and catalase-like activity was positively correlated with sperm count, sperm motility and sperm morphology. Oligoasthenoteratospermic men with low levels of EPA and DHA can benefit from supplementation with omega-3 FA. More studies are needed to shed more light on this important issue.

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Citations: 370

International Journal of Public Health and Safety received 370 citations as per Google Scholar report

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