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Model Proteins | Open Access Journals
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International Journal of Public Health and Safety

ISSN: 2736-6189

Open Access
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Model Proteins

Protein modeling and experimental protein structure determination go hand in hand and share the long-term aspiration of providing 3D atomic-level information for most, if not all, proteins derivable from their amino acid sequences. Structural genomics is a worldwide effort focussing on the rapid determination of a substantial number of protein structures using high-throughput X-ray crystallography and NMR spectroscopy. Populating the PDB with determined structures, and therefore, homology templates, corresponding to major protein families is essential to first limit and eventually eliminate homology “no go” areas within proteomes, so that most and eventually all of the remaining sequences can be accurately modeled. These new structures will also enrich the de novo methods that sample the PDB.

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Citations: 370

International Journal of Public Health and Safety received 370 citations as per Google Scholar report

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