To assess the relative efficacy of high dose myeloablative therapy and progenitor cell transport (HDT / PCT) compared to conventional therapy for the treatment of malignancy. Assess the relative cost of HDT / PCT compared to conventional chemotherapy (CC). To assess the efficiency and cost of bone marrow transplantation (BMT) versus the transport of peripheral blood progenitor cells (PBPCT). Studies were identified by searching the following electronic databases until January 31, 1997 inclusive: MEDLINE, EMBASE, Cancerlit, Cochrane Controlled Trials Register and the NHS Economic Evaluation Database. MEDLINE, EMBASE and Cancerlit were searched for RCTs on June 1, 1997 to identify any RCTs that could have been indexed between January and June. The UKCCCR trial register, the Watch Center clinical trial lists and the Data Query physician database were also consulted. The searches in the Science Citation Index and Biossis were not carried out because preliminary investigations revealed that they did not provide any additional useful information. No manual search was carried out because all the journals which were a priori considered by clinical coordinators as potentially important sources of relevant publications were indexed in one or more of the electronic databases sought.
The RCTs and CCTs as well as summaries regarding cord blood use, long-term toxicity and cost-effectiveness were the subject of manual research in conference proceedings from the following organizations: European Hematology Association (1994-1996), EBMT (1992-1997), American Society for Hematology (1992-1996) and the International Society of Experimental Hematology (1992-1996).
Electronic databases were searched using a slightly modified version of the Cochrane collaboration strategy to identify RCTs as well as more general strategies. These strategies were provided in the report.
Editorial: Transplantation Technologies & Research
Editorial: Transplantation Technologies & Research
Commentary: Transplantation Technologies & Research
Commentary: Transplantation Technologies & Research
Letter to Editor: Transplantation Technologies & Research
Letter to Editor: Transplantation Technologies & Research
Editorial: Transplantation Technologies & Research
Editorial: Transplantation Technologies & Research
Review Article: Transplantation Technologies & Research
Review Article: Transplantation Technologies & Research
Scientific Tracks Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
Accepted Abstracts: Pulmonary & Respiratory Medicine
Accepted Abstracts: Pulmonary & Respiratory Medicine
Scientific Tracks Abstracts: Journal of Forensic Research
Scientific Tracks Abstracts: Journal of Forensic Research
Scientific Tracks Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
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