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Journal of Interventional and General Cardiology

ISSN: 2684-4591

Open Access

Current Issue

Volume 5, Issue 4 (2021)

    Research Article Pages: 1 - 4

    Colchicine for Prevention of in Stent Restenosis in Patients with Bare Metal Stents (Colisr-BMS Trial)

    Mohammed Habib

    Background: In stent restenosis has been a considerable major problem with bare-metal stents (BMS). Pharmacological interventions to decrease Instent restenosis (ISR)
    could be of clinical relevance. Colchicine is associated with reduced inflammation and can be a reduced ISR rate when administered to patients after BMS implantation.
    The current study aimed to evaluate the efficacy of colchicine additional to BMS in the prevention of BMS restenosis in patients who underwent percutaneous coronary
    intervention (PCI).
    Methods: The current clinical study was conducted at Gaza city. It involved 90 patients who were scheduled for coronary angioplasty procedure. The patients were divided
    into three groups: The first group, underwent BMS implantation and received colchicine 0.5 mg twice daily for six months. The second group, underwent BMS implantation
    alone. The third group, underwent DES implantation. All the patients were followed up for six months. The primary endpoint was clinical ISR at 6months. Secondary
    endpoints included target vessel revascularization (TVR) and stent thrombosis (ST).
    Results: The mean age of the patients was 60.03 ± 7.8 years. After 6 months follow-up, significant differences were found in clinical ISR rate among the three groups (3%
    for the colchicine group, 23% for BMS alone and 0% for DES group, P=0.005). In addition, There were significant differences in TVR rate (3% for the colchicine group, 27%
    for BMS alone and 0% for DES group, P=0.002). However, there were no significant differences in the rate of stent thrombosis (0% for the colchicine group, 3% for BMS
    alone and 0% for DES group, P= 1).
    Conclusion: Colchicine is associated with reduced ISR and TVR rate when administered to patients who underwent PCI with BMS as compared to BMS alone.
    Keywords: Instent restenosis (ISR) • Colchicine • Thrombosis • Myocardial Infarction • Revascularization

    Case Series Pages: 1 - 3

    Common Indications for IVC Filter Placement in Nigeria: Three Case Series

    Emmanuel Auchi Edafe*, OkoroTeo and Stanley KN

    There are many reasons for Inferior Vena Cava (IVC) filter placement. Even with the expanding lists of indications, most guidelines recommend that contraindications
    to systemic thrombolysis or its failure may necessitate IVC filter placement. The increased use may be due to insertion of retrievable filters. We report three cases with
    indications for IVC filter placement.
    Keywords: Inferior Vena Cava • Echocardiography • Butadiene solution • His D-dimer • Cardioverter defibrillators • Infra-renal segment • Pulmonary Embolism
    Abbreviations: IVC: Inferior Vena Cava • EAE: European Association of Echocardiography • ASE: American Society of Echocardiography • DVT: Deep Vein Thrombosis

    Mini Review Pages: 1 - 4

    Cardioversion Safety? Is It Safe To Say That We Are Doing Enough?

    Mohsen Khatami*, Marita Knudsen Pope, Sophie Le Page, Petra Radic, Valentina Schirripa, Irene Grundvold and Dan Atar

    There is a significant periprocedural hazard of thromboembolic occasions in atrial fibrillation patients going through cardio-variant, and treatment with anticoagulants is
    accordingly a sign of cardioversion well being. In view of review sub-bunch examinations and imminent investigations, non-nutrient K enemies of coagulants are in any event
    as proficient as nutrient K-foes in forestalling thromboembolic intricacies after cardiovariant. The danger of thromboembolic intricacies after vehicle dioversion particularly
    relies upon the comorbidities in a given patient, and particularly cardiovascular breakdown, diabetes, and age. >75 years convey a uniquely expanded danger. Cardioversion
    has been viewed as protected inside a 48-h time window after beginning of atrial fibrillation without earlier treatment with anticoagulants, however late investigations have
    set this training into question dependent on for example flighty presentation appraisal of atrial fibrillation. Consequently, a straightforward and more functional methodology
    is here suggested, where early cardioversion is performed uniquely in haemodynamically temperamental patients.
    Keywords: Cardioversion • Safety • Atrial fibrillation • Anticoagulation • Stroke prevention

    Mini Review Pages: 1 - 2

    Myocardial Infarction(MI) in Covid-19 Era

    Vincenzo De Simone*, Antonio Mugnolo, Alberto Zamboni and Giorgio Morando

    February 21, 2020 imprints the start of an emotional time in Italy. Affirmations for intense myocardial dead tissue were fundamentally decreased during the COVID-19
    pandemic, with an equal expansion in casualty and confusion rates. Clinic affirmations because of ST-section rise myocardial localized necrosis of patients living in our
    well-being area, were screened between February 21st and May third, finish of lockdown stage one, and contrasted with a similar time period of 2019. We enlisted 32
    confirmations contrasted with 57 in a similar 2019 time-frame, representing a huge decrease (- 43.9%; p < 0.01). A critical postponement (> 24 hrs) in looking for first clinical
    contact after manifestations beginning has been enlisted in 42.5% of this current year patients (middle time 17 hours, interquartile range 9.5-30) contrasted with 7.1%
    (middle time 6 hours, interquartile range 4-9) in a similar time of 2019. The time factor affected the clinical advancement of our patients, not just in the intense stage, so we
    experienced all the more regularly states of cardiogenic stun with the requirement for hemodynamic and respiratory help, yet in addition in the resulting intra-emergency
    clinic course we recorded inconveniences unmistakably identified with huge infarct estimates because of patient's postpone like left ventricular thrombus.

    Keywords: Covid19 • STEMI • Patientdelay • Left ventricular thrombus

    Short Communication Pages: 1 - 2

    Effects of Liquor Consumption on the Cardiovascular System: In Vino Veritas

    Simone Persampieri*, Alon Schaffer, Leonardo De Martino, FedericaValli and Alessandro Lupi

      

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