Department of R&D and Clinical Testing, Complife Italia S.r.l., 27028 San Martino Siccomario, PV, Italy
 Research   
								
																Efficacy of Oryza Sativa L. (Black Rice) and Opuntia Ficus Indica L. Blend in Men with Androgenetic Alopecia: A Randomized, Double−Blind, Placebo−Controlled Clinical Trial 
																Author(s): Enza Cestone, Eleonora Spartà, Vincenzo Nobile*, Vincenzo Zaccaria*, Francesco Pappalardo, Violetta Insolia, Giuseppe Antonio Malfa, Daniela Buonocore and Maurizia Dossena             
								
																
						 Androgenetic Alopecia (AGA) is a progressive hair loss type affecting up to 80% of men and 50% of women. The putative mechanisms in the 
  pathogenesis of AGA include microinflammation, premature cell senescence, oxidative stress, follicle vascular changes and altered sensitivity of 
  hair follicles to androgens. A randomized, double-blind, placebo-controlled trial was carried out on 86 male subjects with AGA from II to III vertex 
  (Hamilton-Norwood). Product efficacy was measured after 3, 6 months of product intake and 1-month post-supplementation. The hair cycle 
  parameters measurement by phototricogram were integrated by the global photography assessment and the self-assessment questionnaire. The 
  results showed an increase of the total hair density and the % of hair in anagen phase with a simultaneous decrease in the % of hair in telogen 
  phase; as consequence the a.. Read More»
						  
																DOI:
								10.37421/2471-9323.2023.9.207															  
Journal of Cosmetology & Trichology received 180 citations as per Google Scholar report