Journal of Molecular Histology & Medical Physiology

ISSN: 2684-494X

Open Access

Thomas Pichler

Department of Oncology, Medical University of Graz, Graz, Austria

  • Case Report   
    Diagnosis of Testicular Germ Cell Tumors in Male
    Author(s): Thomas Pichler*

    In younger men, testicular germ cell tumours (TGCTs) are the most often identified cancers. Traditional tumour markers, such as -fetoprotein, provide assistance for tracking the progression and recurrence of disease (AFP). It has been noted that elevated levels of AFP, which are biologically produced in the liver and can be found in patients with testicular cancer as well as under other benign liver disorders, might lead to a mistaken interpretation of the clinical course of TGCT. In freshly diagnosed TGCTs, a group of stem cell-associated microRNAs have been shown to outperform conventional tumour markers, however it has never been shown how well these microRNAs can distinguish between particular and non-specific AFP increases. We describe a patient with chronic hepatitis B, normal liver-related blood values and increased AFP levels who also had a primary TGCT.. Read More»
    DOI: 10.37421/2684-494X.2022.7.44

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Citations: 25

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