Journal of Blood & Lymph

ISSN: 2165-7831

Open Access

Lutz Gürtler

Max Von Pettenkofer Institut, Ludwig-Maximilians University (LMU), Munich, Germany

  • Mini Review   
    COVID-19 Convalescent Plasma: No Definite Answer Yet
    Author(s): Rainer Seitz*, Lutz Gürtler and Wolfgang Schramm

    The COVID-19 pandemic so far caused millions of deaths, and the therapeutic options for high-risk patients are far from being satisfactory. Active immunization by vaccines against SARS-CoV-2 spike protein provides good protection from a severe course of COVID-19. It has been explored in numerous clinical trials, whether also passive immunization by transfusion of convalescent plasma could positively influence the course of COVID-19. Large randomized clinical trials failed to demonstrate a benefit for patients with advanced disease. However, the antibody dose and timing of transfusion might have contributed to this negative result. Randomized clinical trials are necessary to make evidence-based progress in the development of therapeutic options, and this holds true also for “natural” concepts. However, even highquality trials are just a tool to test predef.. Read More»
    DOI: 10.37421/2165-7831.2021.11.265

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Google Scholar citation report
Citations: 443

Journal of Blood & Lymph received 443 citations as per Google Scholar report

Journal of Blood & Lymph peer review process verified at publons

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