Journal of Blood & Lymph

Department of Neurology, University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam

Publications

• Short Communication   
  Discover the Role of Calorie Restriction in Cancer Immunotherapy
  Author(s): Dung Tien Nguyen*, Bang Ngoc Dao and Thang Ba Ta
  
  Nowadays, the development of cancer immunotherapy has brought breakthrough results in treatment. However, understanding of the limitations of this therapy remains unclear. While the significant role of dietary energy intake in regulating cancer progression and host immunity is widely acknowledged, the impact of dietary Calorie Restriction (CR) on anti-tumor immune responses remains uncertain. Investigating this, we utilized an immunogenic B16 melanoma cell expressing ovalbumin (B16-OVA) to assess the effect of the CR diet on tumor growth and host immune responses. Furthermore, we evaluated whether the CR diet influenced the effectiveness of cancer immunotherapy, specifically anti-PD-1 monoclonal antibody (anti-PD-1 Ab) treatment. Our findings indicate that the CR diet notably decelerated B16-OVA tumor growth without altering CD4+ and CD8+ T cell infiltration into.. Read More»
  DOI: 10.37421/2165-7831.2025.15.342

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