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Nuclear Medicine & Radiation Therapy

ISSN: 2155-9619

Open Access

Paul C Kruger


South Korea

Publications
  • Research Article
    Iodine-131 Rituximab Radioimmunotherapy: Durable Control of Follicular Lymphoma
    Author(s): Paul C Kruger, David JL Joske and Harvey Turner JPaul C Kruger, David JL Joske and Harvey Turner J

    Abstract Aims: We evaluated the response and toxicity, after long-term follow up of Iodine-131 rituximab radioimmunotherapy in patients with follicular lymphoma under the routine clinical care of a single hematologist over a period of 12 years. Materials and methods: Patients received 131I-rituximab radioimmunotherapy according to a standard, personalized dosimetry protocol predicated upon a prescribed whole body radiation absorbed dose of 0.75Gy. Four doses of maintenance rituximab were subsequently administered over 12 months.   Results: Response rate was 97% with 24(77%) patients experiencing a complete remission confirmed on 18F-fluorodeoxyglucose positron emission tomography-computerized tomography scan. The cohort of 3 patients with duodenal lymphoma all achieved complete remission lasting 4-5 years. Disclosure statement: T.. Read More»
    DOI: 10.4172/2155-9619.1000191

    Abstract PDF

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Citations: 706

Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report

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