Journal of Blood & Lymph

Kuruppumullage SDL

Publications

• Case Report
  A Rare Case of Light Chain Myeloma with Amyloidosis
  Author(s): Gunawardena D and Kuruppumullage SDLGunawardena D and Kuruppumullage SDL
  
  Background: Multiple myeloma is characterized by neoplastic proliferation of a single clone of plasma cells producing a monoclonal immunoglobulin. It comprises about 1% of all malignant tumours and 10-15% of haematopoietic neoplasms. Light chain myeloma accounts for up to one-fifth of all cases of myeloma and is typified by only a light chain in the serum or urine, lacking expression of the immunoglobulin heavy chain. Amyloidosis is characterized by extracellular deposition of insoluble fibrillar protein called amyloid, in various tissues and organs. Light chain (LC) amyloidosis is the most common form of systemic amyloidosis and it complicates about 10% of cases of myeloma. When multiple myeloma is complicated by LC amyloidosis, the myeloma is typically diagnosed before or around the time of the diagnosis of amyloidosis. Case presentation: We r.. Read More»
  DOI: 10.4172/2165-7831.1000151

  Abstract PDF