China						                            
                            
						
 Research Article
												Six Degree-of-Freedom Image Guidance for Frameless Intracranial Stereotactic RadioSurgery with kilo-voltage Cone- Beam CT 						
Author(s): Zheng Chang, Zhiheng Wang, Jinli Ma, Q. Jackie Wu, Scott Senick, Ryan McMahon, John P. Kirkpatrick and Fang-Fang YinZheng Chang, Zhiheng Wang, Jinli Ma, Q. Jackie Wu, Scott Senick, Ryan McMahon, John P. Kirkpatrick and Fang-Fang Yin             
						
												
				 Abstract Purpose: To investigate localization accuracy for frameless intracranial stereotactic-radiosurgery using 2D orthogonal planar imaging and 3D cone-beam CT (CBCT) in 6-degree-of-freedom (6-DOF).
Methods and Materials: In a phantom study, a target ball phantom was used to perform a Winston-Lutz test and to verify coincidence of imaging isocenter and radiation isocenter. A head phantom was placed with pre-defined positions and imaged with CBCT to test imaging accuracy. In a patient study, one hundred patients were included. Patients were initially positioned with a thermoplastic frameless mask system and then aligned with orthogonal planar imaging and CBCT. The setup discrepancies were quantitatively analyzed.
Results: Phantom experiments showed discrepancies in root-mean-square were 1.6mm translationally and 0.5&.. Read More»
				  
												DOI:
												 10.4172/2155-9619.1000101 
																	  
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report