Nuclear Medicine & Radiation Therapy

Charles A Kunos

Publications

• Case Report
  2-[¹⁸F]Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Definition of Lung Targets in Vero Stereotactic Body Radiation Therapy Workflow
  Author(s): Charles A Kunos and John P ShanahanCharles A Kunos and John P Shanahan
  
  This retrospective study explored 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) as an aid in target delineation among a first-group of five patients with single or multiple moving lung tumors planned for Vero stereotactic body radiation therapy (SBRT). Computed tomography (CT)-based free-breathing, end-inspiration, and end-expiration lung target volumes generated a single internal target volume (ITV). ITVs were compared to a thresholded 40% maximum standard uptake value FDG-PET target volume (CTVpet), a contour assumed to be a surrogate for lung target motion during quiet breathing. Planning target volumes (PTV) and relevant lung planning constraints determined clinical execution of Vero SBRT. A mean 28% PTV expansion by adding in a CTVpet contour to the CT-based ITV converted two (40%) of five cases from SBRT fractionation (40 Gy in four every other day fract.. Read More»
  DOI: 10.4172/2155-9619.1000227

  Abstract PDF