Transplantation Technologies & Research

The thickest of the three membranes that make up a foetal body is the amniotic membrane (AM), sometimes known as an amnion. A single layer of amnion epithelial cells anchored to a thick basement membrane, as well as an avascular stromal matrix, make up this semi-transparent membrane. In addition to integrin, fibronectin and laminin, it has been shown that the human amniotic membrane also includes collagen types IV and VII, as seen with the Bowman membrane cornea. Its earliest documented usage in ophthalmology was by De Rotth, who utilised the foetal membrane (both amniotic membrane and chorion) to correct epithelial conjunctival abnormalities in patients with symblepharon. It was first used therapeutically in 1910 by Davis for skin transplantations.

Hair loss affects both men and women and, for many people, profoundly impacts psychosocial function and psychological well-being. Few other physical signs of aging demonstrate such direct correlation with self-esteem and self-worth. Hair has long been associated with youth, vitality and health; and our individual hair styles frame our faces and communicate information about our unique personalities.

AMR, or active and persistent antibody-mediated rejection, is a frequent reason for graft failure. The prognostic indicators for this condition are unclear. Our goal was to identify the demographic, histological and clinical characteristics of transplant recipients who had AMR and to assess how these traits and antirejection therapy options affected graft survival.