This research sought to assess the effect of the risk of chicken death on the production of commercial broiler farms in Douala, the economic capital of the Republic of Cameroon. More specifically this work aimed to assess the effect of (the risk of disease outbreak, the risk of heat or thermal stress and the risk of technical errors) on the production of commercial broiler farms in Douala and to make some suggestions to stakeholders of the poultry industry on how to monitor and control this risk. A sample of 254 poultry farm managers and their assistants in the city of Douala were selected using the purposive sampling technique to take part in this study. Primary data was gotten through the use of a structured questionnaire, interviews and non-participant observations, while secondary data was gotten through magazines, newspapers, published articles and official reports. Statistical Package for Social Sciences (IBM SPSS 20) was used to run the major statistics from the data collected. The coefficient of multiple determinations (R2) was used to assess the relationships between risks management and broiler production. The results of this study revealed that, there is a negative effect of (the risk of disease outbreak, the risk of heat or thermal stress and the risk of technical errors) on the production of commercial broiler farms in Douala. The study therefore recommended among others to the farmers that, they should make sure that strict hygienic conditions and biosecurity rules are implemented in the farm in order to avoid disease occurrence and spread and to equally follow the instructions of the animal health professionals concerning vaccination, preventive treatments and density of birds per meter square.