Journal of Cosmetology & Trichology

Multiethnic Clinical-Instrumental Evaluation Of The Efficacy Of A Nutritional Supplement On Hair Shedding And Hair Health: A Randomized, Placebo-Controlled Clinical Trial

Abstract

Xiaoyan Yu, Gloria Roveda, MediAbout s.r.l. Medical Department* and Vincenzo Nobile

Hair loss and reduced hair quality are common concerns in both men and women, often associated with Telogen Effluvium (TE), a form of nonscarring alopecia characterized by diffuse, acute hair shedding. A novel dietary supplement containing plant-derived oils and phytosterols (Beaulixir®) has shown beneficial effects on scalp coverage and perceived hair loss reduction. This multicentric, randomised, double-blind, placebo-controlled study evaluated the efficacy and safety of two daily doses (400 mg and 600 mg) of Beaulixir® in improving hair parameters in 72 healthy Caucasian and Asian men and women (18?65 years) with acute TE (<6 months? onset) and ?15% telogen hairs at inclusion. Participants received either 400 mg/day, 600 mg/day, or placebo for 84 days. Efficacy endpoints included hair density, anagen/telogen ratio, thickness, brightness and elasticity, assessed by phototrichogram, spectrophotometry and dynamometry. Perceived efficacy was evaluated using a self-assessment questionnaire. At day 84, both treated groups showed a significant increase in total hair density (600 mg: +11.1%; 400 mg: +8.1%) and thickness (600 mg: +2.2%; 400 mg: +1.5%) vs. baseline. The proportion of anagen hairs increased, while telogen hairs decreased. Hair brightness improved significantly in both active groups vs. placebo, with Caucasian subjects also showing enhanced elasticity. The supplement was positively rated by most participants and no serious adverse events occurred. Beaulixir® significantly improved hair density, thickness, brightness and elasticity in subjects with acute TE, demonstrating good safety and tolerability as a nutritional approach to support hair quality and reduce shedding.