Journal of Surgery

ISSN: [Jurnalul de chirurgie]
ISSN: 1584-9341

Open Access

Current Issue

Volume 18, Issue 11 (2022)

    Mini Review Pages: 1 - 2

    Cardiac Surgery during the COVID-19 Pandemic

    Adrian Lobontiu*

    DOI: 10.37421/1584-9341.2022.18.66

    There is a dearth of information regarding surgical services and patient outcomes during a pandemic because the major focus is kept on the pandemic itself and critical care. The majority of the small studies focusing on the outcomes of Covid-19 positive patients after various surgical procedures, such as thoracic and orthopaedic surgery, make up the currently available Covid-19 evidence. According to these preliminary investigations, surgery increases the chance of death in people who have Covid-19 and the disease's progression in those who are only incubating it. More recently, the COVIDSurg partnership has reported on 1128 surgical patients with a Covid-19 diagnosis (pre- or post-surgery) across 235 hospitals in 24 countries with a variety of therapeutic indications.

    Mini Review Pages: 1 - 2

    Lung Cancer Surgery for Patients on Hemodialysis

    Andronic Constantin*

    DOI: 10.37421/1584-9341.2022.18.65

    Surgery patients who are on dialysis are in a high-risk category. The results of major thoracic surgical procedures in dialysis patients have only been studied in a small number of studies. In patients receiving haemodialysis, we assessed the results of pulmonary resection for non-small cell lung cancer .Surgery involving dialysis patients is a high-risk situation that calls for meticulous postoperative management. Patients on dialysis are frequently not deemed eligible for major surgical procedures due to their higher risk of perioperative problems linked with electrolyte imbalance, haemorrhage, infection, and hemodynamic instability. Due to this, only a small number of studies have assessed the results of major thoracic surgical procedures in patients who are receiving dialysis for chronic kidney disease .This study's objective was to assess the postoperative results of pulmonary resection for non-small cell lung cancer in patients who are receiving haemodialysis because of chronic kidney disease in terms of complications and survival.

    Volume 20, Issue 1 (2024)

      Research Article Pages: 1 - 7

      NVP-231, a Ceramide Kinase Inhibitor, Causes M Phase Arrest and Consequent Cell Death to Stop the Growth of Breast and Lung Cancer Cells

      Hari Prasad Sonwani*

      DOI: 10.37421/1584-9341.2024.20.126

      Context and objective: The production of ceramide-1-phosphate, which is catalysed by ceramide kinase (CerK), may influence a number of cellular processes, including inflammation and cell division. Here, we looked at how the newly created CerK inhibitor NVP-231 affected the viability and proliferation of cancer cells, as well as the function of cell cycle regulators linked to these reactions.

      Experimental methodology: Gradually increasing concentrations of NVP-231 were applied to the lung cancer cell line NCI-H358 and the breast cancer cell line MCF-7 in order to measure DNA synthesis, colony formation, and cell death. The cell cycle distribution of the cells was analyzed using flow cytometry, and alterations in the expression and activation of cell cycle regulators were found using Western blot analysis.

      Important findings: NVP-231 decreased DNA synthesis, colony formation, and cell survival in both cell lines in a concentration-dependent manner. Additionally, it caused apoptosis, as seen by elevated caspase-3 and caspase-9 cleavage and DNA fragmentation. NVP-231 reduced the proportion of cells in the S phase and caused an M phase arrest with an elevated mitotic index, as shown by increased histone H3 phosphorylation, according to cell cycle analysis. When staurosporine was added to NVP-231 therapy, the impact on the cell cycle became even more noticeable. Lastly, siRNA-induced down-regulation of CerK sensitized cells to staurosporine-induced apoptosis, although overexpression of CerK protected against this process.

      Conclusions and significance: our findings reveal for the first time the critical function that CerK plays in the regulation of the M phase in cancer cells. We propose that CerK be specifically inhibited, with the use of medications like NVP-231, in conjunction with standard pro-apoptotic treatment.

      Mini-Review Pages: 1 - 2

      The Art and Science of Surgery: Bridging Precision and Compassion

      Dorata Lewandowsk*

      DOI: 10.37421/1584-9341.2024.20.128

      Surgery, often regarded as the pinnacle of medical intervention, embodies a delicate balance between meticulous science and intuitive artistry. In this article, we delve into the intricate relationship between the technical precision demanded by surgical procedures and the humanistic touch required for compassionate care. Through exploring the evolution of surgical practices, the integration of advanced technologies, and the essential role of empathy, we illuminate the multifaceted nature of surgery as both an art and a science.

      Mini Review Pages: 1 - 2

      Aesthetic Reconstructive Surgery Techniques: Restoring Beauty, Confidence and Function

      Gairioa H. Itmua*

      DOI: 10.37421/1584-9341.2024.20.129

      Aesthetic reconstructive surgery represents a remarkable intersection of artistry and medical science, where innovative techniques are employed to restore not only physical appearance but also psychological well-being. In this article, we explore the evolution of aesthetic reconstructive surgery, highlighting advanced techniques used to address a wide range of conditions, from congenital anomalies to traumatic injuries and postsurgical deformities. Through a lens of compassion and precision, we delve into the transformative impact of these procedures on patients' lives, emphasizing the holistic approach that considers both the aesthetic and functional aspects of reconstruction. Keywords: aesthetic reconstructive surgery, plastic surgery, reconstructive techniques, cosmetic enhancement, patient satisfaction.

      Mini Review Pages: 1 - 2

      Advancements in Reconstructive Surgery: Pioneering Techniques for Restoration and Renewal

      Gairioa H. Itmua*

      DOI: 10.37421/1584-9341.2024.20.130

      Reconstructive surgery has witnessed remarkable advancements in recent years, revolutionizing the field and offering new hope to patients facing traumatic injuries, congenital anomalies, and the aftermath of disease. In this article, we explore the latest innovations in reconstructive surgery, including tissue engineering, microsurgery, and regenerative medicine. Through a comprehensive overview of cutting-edge techniques and emerging trends, we highlight the transformative impact of these advancements on patient outcomes and quality of life. Keywords: reconstructive surgery, advancements, tissue engineering, microsurgery, regenerative medicine, patient outcomes.

      Mini Review Pages: 1 - 2

      Pediatric Surgical Oncology: Advancements, Challenges and Empowering Futures

      Robert Clan*

      DOI: 10.37421/1584-9341.2024.20.132

      Pediatric Surgical Oncology is a specialized field dedicated to the diagnosis and treatment of cancer in children. This article explores the unique challenges and advancements in pediatric oncology surgery, covering topics such as diagnosis, surgical techniques, postoperative care, and longterm outcomes. Key areas of focus include multidisciplinary collaboration, minimally invasive approaches, and personalized treatment plans. By understanding the complexities of pediatric surgical oncology, healthcare professionals can work together to improve outcomes and quality of life for young cancer patients.

      Mini Review Pages: 1 - 2

      Infectious Complications in Emergency General Surgery: A Mini Review

      Crotan D. Martin*

      DOI: 10.37421/1584-9341.2024.20.133

      Emergency General Surgery (EGS) encompasses a broad spectrum of surgical procedures performed urgently to address acute conditions such as trauma, abdominal emergencies, and infections. Despite advancements in surgical techniques and perioperative care, infectious complications remain a significant concern in EGS. These infections not only prolong hospital stays but also escalate healthcare costs and burden patients with additional morbidity and mortality. Thus, a comprehensive understanding of the factors influencing infectious complications and the implementation of evidence-based interventions are imperative to improve outcomes in emergency general surgery. This delves deeper into the nuances of infectious complications in EGS, aiming to provide insights that inform clinical practice and enhance patient care.

      Volume 17, Issue 2 (2021)

        Editorial Pages: 1 - 3

        Young Researchers Forum - Young Scientist Awards ENT Surgery-2021.

        Hadi Nural

        Surgery Conference Committee is glad to announce “International Conference on ENT Surgery” August 17 -18, 2020 in London, UK by focus on the theme: “Reviving new aspects in ENT Surgery”. Conference series organize 3000+ Global Events inclusive of 2000+ Conferences, 500+ Workshops and 500+ symposiums on various topics of Science and Technology across the globe with support from 1,000 more scientific societies and Publishes 900+ Open access journals which contains over 50,000 eminent personalities, reputed Scientists as Editorial Board Members. Prestigious Award for Young Research’s at ENT Surgery 2020 - Discovering New Exploration in Surgery field. Surgery Conference Committee is intended to honour prestigious award for talented Young researchers, scientists, Young Investigators, Post-Graduate students, Post-doctoral fellows, Trainees, Junior faculty in recognition of their outstanding contribution towards the conference theme. The Young Scientist Awards make every effort in providing a strong professional development opportunity for early career academicians by meeting experts to exchange and share their experiences on all aspects of Surgery.

        Young Research Forum Pages: 1 - 3

        Young Researchers Forum - Young Scientist Awards Plastic Surgery-2021.

        Hadi Nural

        Surgery Conference Committee is glad to announce “5 th Global Meeting on Plastic, Aesthetic and Reconstructive Surgery” August 17 -18, 2020 in London, UK by focus on the theme: “Reviving new aspects in Plastic Surgery” Plastic Surgery Conf 2020 developments are maintaining their momentum. Surgery Conference program delves into strategic discussions Conference series organize 3000+ Global Events inclusive of 2000+ Conferences, 500+ Workshops and 500+ symposiums on various topics of Science and Technology across the globe with support from 1,000 more scientific societies and Publishes 900+ Open access journals which contains over 50,000 eminent personalities, reputed Scientists as Editorial Board Members.

        Young Research Forum Pages: 1 - 2

        Young Researchers Forum - Young Scientist Awards Surgeons Meet 2021.

        Ergun Demirsoy

        Surgery is a medical specialty in which different operative manual and instrumental techniques are applied on a patient to investigate or to treat some pathological conditions like disease or injury, to improve bodily function or appearance and repair unwanted ruptured areas. The act of surgical procedure is performed by a surgical team consisting of surgeons, surgeon’s assistant, anaesthetist, circulating nurse and surgical technologists. Surgeons and Physicians diagnose and treat illness and injuries in both humans and animals.

        Editorial Pages: 1 - 5

        Pediatrics and Neonatology 2020 scheduled at New York, USA during 07-08 October 2021.

        Suchi Spore

        We deliver together industrial executives, neonatology pharma and health care sectors making the conference an excellent platform to network, share views and appreciation through interactive discussions. Worldwide, under-five mortality has considerably diminished over the closing decade from 90 deaths per 1,000 stay births in 1990, to forty-six per 1,000 in 2013. However, neonatal mortality has now not saved pace. Today, newborn deaths account for 44% of under-five deaths worldwide. Nearly a quarter of these deaths are triggered with the aid of unfavorable intra-partum events; a large percentage of these children die in their first 24 hours of life (Figure 1). Neonatal resuscitation can help ward off new child loss of life with the aid of supporting to set up adequate respiratory and circulation when newborns are unable to acquire these on their own. It is estimated that between 5%-10% of newborns at beginning require resuscitation.

        Editor Note Pages: 1 - 1

        Note for Journal of Surgery [Jurnalul de chirurgie].

        Isabelle Gomez

        I am pleased to mention that during the year 2019, all issues of volume 15 were published online well within the time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. Journal of Surgery [Jurnalul de chirurgie] during this year also brought out 4th Global Meeting on Plastic, Aesthetic and Reconstructive Surgery, which consisted of ~11 abstracts. The JCR Impact factor of JOS for the year 2018 was 1.91, while the current SJR index dropped to 0.256. The H-index of the journal, however, increased to 50 and JOS ranked first among all journals in the field of Surgical Sciences published in Indi a, 2nd in Asia and 48th in the world.

        Volume 17, Issue 7 (2021)

Google Scholar citation report
Citations: 288

Journal of Surgery received 288 citations as per Google Scholar report

Journal of Surgery peer review process verified at publons

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