DOI: 10.37421/1584-9341.2022.18.69
The authors based on the analysis of literature reports have concluded that the danger of intraabdominal complications after IPOM is exaggerated. Tension-free intraperitoneal plasty with synthetic endoprostheses in abdominal wall hernias is a simple and reliable surgical approach. The results of studies as well as the meta-analysis of the series presented in the Literature, indicate that the IPOM may be a feasible, safe and effective procedure in the treatment of recurrent and bilateral hernias or when a hernia repair is performed during other laparoscopic procedures. The IPOM has in fact been shown to be faster and easier than the other more commonly performed laparoscopic hernioplasties (TAPP and TEP). This data may also suggest utilizing this technique in particular cases of primitive hernia such as very active young males or heavy duty workers. However the limited series and the short follow-up ask for randomized prospective long term studies to definitely ascertain the true incidence of recurrence and therefore the effectiveness of this attractive procedure.
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The majority of cardiac surgery in recent times has involved a median sternotomy and cardiopulmonary bypass. However, as the use of minimally invasive procedures in cardiovascular surgery increases, this paradigm is shifting. Surgeons now have the ability to carry out a wide range of intricate procedures with fewer incisions and, in some instances, without the use of cardiopulmonary bypass thanks to advancements in patient evaluation, instrumentation and surgical technique. Minimally invasive cardiac surgery ought to be widely practiced because patients want less invasive procedures and the literature supports reduced blood loss, shorter hospital stays, reduced postoperative pain and improved cosmesis. In this section, we discuss the various approaches and incisions currently utilized in minimally invasive cardiovascular surgery.
DOI: 10.37421/1584-9341.2022.18.71
Women who seek breast augmentation have a high prevalence of breast asymmetries. However, it is unknown how common breast asymmetries are among women undergoing other kinds of breast surgeries. In a prospective plastic surgery database, the measurements of the breasts of consecutive women who were being evaluated for breast plastic surgery but had not had any prior breast surgery were recorded. They were arranged into three gatherings as per the introducing bosom issue: macromastia, ptosis and hypoplastic breasts Correlations were made between the right and left half of every patient with respect to the evenness of the areola complex (size and position), bosom hill and chest wall.
DOI: 10.37421/1584-9341.2022.18.63
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Western University's Department of Surgery, which was established in 1881, is one of the largest departments in the Schulich School of Medicine & Dentistry. The department, which has eight divisions, has grown a lot in the past ten years. The J.C. Kennedy Chair in Orthopaedic Surgery, the Sandy Kirkley Chair in Musculoskeletal Research, the Graham King Musculoskeletal Research Chair and the Ray and Margaret Elliott Chair in Surgical Innovation are just a few of the endowed chairs that have been established in recent years. The department's international visibility has significantly increased as a result of international initiatives in education, research and surgical advancements. The department has become a sought-after training opportunity due to its long history of surgical innovation and patient-centered care.
DOI: 10.37421/1584-9341.2022.18.60
Machemer's introduction of the intraocular vitrectomy instrument has made remarkable progress in vitreoretinal surgery, making it possible to surpass the limits of human physiologic capabilities. Robotic technologies have been looked into as a way to get around the limitations of perception, tremor and dexterity. Right now, some of these developments are getting close to being practical for clinical use. The research has revealed four distinct categories of robotic systems: magnetic guidance robots, hand-on-hand robotic systems, teleoperated robotic systems and instruments with intrinsic robotic assistance For safe and cost-effective clinical deployment of robotic systems in vitreoretinal surgery, this review examines the advancements that have been made as well as the needs that remain.
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There is a dearth of information regarding surgical services and patient outcomes during a pandemic because the major focus is kept on the pandemic itself and critical care. The majority of the small studies focusing on the outcomes of Covid-19 positive patients after various surgical procedures, such as thoracic and orthopaedic surgery, make up the currently available Covid-19 evidence. According to these preliminary investigations, surgery increases the chance of death in people who have Covid-19 and the disease's progression in those who are only incubating it. More recently, the COVIDSurg partnership has reported on 1128 surgical patients with a Covid-19 diagnosis (pre- or post-surgery) across 235 hospitals in 24 countries with a variety of therapeutic indications.
DOI: 10.37421/1584-9341.2022.18.65
Surgery patients who are on dialysis are in a high-risk category. The results of major thoracic surgical procedures in dialysis patients have only been studied in a small number of studies. In patients receiving haemodialysis, we assessed the results of pulmonary resection for non-small cell lung cancer .Surgery involving dialysis patients is a high-risk situation that calls for meticulous postoperative management. Patients on dialysis are frequently not deemed eligible for major surgical procedures due to their higher risk of perioperative problems linked with electrolyte imbalance, haemorrhage, infection, and hemodynamic instability. Due to this, only a small number of studies have assessed the results of major thoracic surgical procedures in patients who are receiving dialysis for chronic kidney disease .This study's objective was to assess the postoperative results of pulmonary resection for non-small cell lung cancer in patients who are receiving haemodialysis because of chronic kidney disease in terms of complications and survival.
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DOI: 10.37421/1584-9341.2024.20.126
Context and objective: The production of ceramide-1-phosphate, which is catalysed by ceramide kinase (CerK), may influence a number of cellular processes, including inflammation and cell division. Here, we looked at how the newly created CerK inhibitor NVP-231 affected the viability and proliferation of cancer cells, as well as the function of cell cycle regulators linked to these reactions.
Experimental methodology: Gradually increasing concentrations of NVP-231 were applied to the lung cancer cell line NCI-H358 and the breast cancer cell line MCF-7 in order to measure DNA synthesis, colony formation, and cell death. The cell cycle distribution of the cells was analyzed using flow cytometry, and alterations in the expression and activation of cell cycle regulators were found using Western blot analysis.
Important findings: NVP-231 decreased DNA synthesis, colony formation, and cell survival in both cell lines in a concentration-dependent manner. Additionally, it caused apoptosis, as seen by elevated caspase-3 and caspase-9 cleavage and DNA fragmentation. NVP-231 reduced the proportion of cells in the S phase and caused an M phase arrest with an elevated mitotic index, as shown by increased histone H3 phosphorylation, according to cell cycle analysis. When staurosporine was added to NVP-231 therapy, the impact on the cell cycle became even more noticeable. Lastly, siRNA-induced down-regulation of CerK sensitized cells to staurosporine-induced apoptosis, although overexpression of CerK protected against this process.
Conclusions and significance: our findings reveal for the first time the critical function that CerK plays in the regulation of the M phase in cancer cells. We propose that CerK be specifically inhibited, with the use of medications like NVP-231, in conjunction with standard pro-apoptotic treatment.
DOI: 10.37421/1584-9341.2024.20.127
DOI: 10.37421/1584-9341.2024.20.128
Surgery, often regarded as the pinnacle of medical intervention, embodies a delicate balance between meticulous science and intuitive artistry. In this article, we delve into the intricate relationship between the technical precision demanded by surgical procedures and the humanistic touch required for compassionate care. Through exploring the evolution of surgical practices, the integration of advanced technologies, and the essential role of empathy, we illuminate the multifaceted nature of surgery as both an art and a science.
DOI: 10.37421/1584-9341.2024.20.129
Aesthetic reconstructive surgery represents a remarkable intersection of artistry and medical science, where innovative techniques are employed to restore not only physical appearance but also psychological well-being. In this article, we explore the evolution of aesthetic reconstructive surgery, highlighting advanced techniques used to address a wide range of conditions, from congenital anomalies to traumatic injuries and postsurgical deformities. Through a lens of compassion and precision, we delve into the transformative impact of these procedures on patients' lives, emphasizing the holistic approach that considers both the aesthetic and functional aspects of reconstruction. Keywords: aesthetic reconstructive surgery, plastic surgery, reconstructive techniques, cosmetic enhancement, patient satisfaction.
DOI: 10.37421/1584-9341.2024.20.130
Reconstructive surgery has witnessed remarkable advancements in recent years, revolutionizing the field and offering new hope to patients facing traumatic injuries, congenital anomalies, and the aftermath of disease. In this article, we explore the latest innovations in reconstructive surgery, including tissue engineering, microsurgery, and regenerative medicine. Through a comprehensive overview of cutting-edge techniques and emerging trends, we highlight the transformative impact of these advancements on patient outcomes and quality of life. Keywords: reconstructive surgery, advancements, tissue engineering, microsurgery, regenerative medicine, patient outcomes.
DOI: 10.37421/1584-9341.2024.20.131
DOI: 10.37421/1584-9341.2024.20.132
Pediatric Surgical Oncology is a specialized field dedicated to the diagnosis and treatment of cancer in children. This article explores the unique challenges and advancements in pediatric oncology surgery, covering topics such as diagnosis, surgical techniques, postoperative care, and longterm outcomes. Key areas of focus include multidisciplinary collaboration, minimally invasive approaches, and personalized treatment plans. By understanding the complexities of pediatric surgical oncology, healthcare professionals can work together to improve outcomes and quality of life for young cancer patients.
DOI: 10.37421/1584-9341.2024.20.133
Emergency General Surgery (EGS) encompasses a broad spectrum of surgical procedures performed urgently to address acute conditions such as trauma, abdominal emergencies, and infections. Despite advancements in surgical techniques and perioperative care, infectious complications remain a significant concern in EGS. These infections not only prolong hospital stays but also escalate healthcare costs and burden patients with additional morbidity and mortality. Thus, a comprehensive understanding of the factors influencing infectious complications and the implementation of evidence-based interventions are imperative to improve outcomes in emergency general surgery. This delves deeper into the nuances of infectious complications in EGS, aiming to provide insights that inform clinical practice and enhance patient care.
DOI: 10.37421/1584-9341.2024.20.134
DOI: 10.37421/1584-9341.2024.20.135
Hadi Nural
Surgery Conference Committee is glad to announce “International Conference on ENT Surgery” August 17 -18, 2020 in London, UK by focus on the theme: “Reviving new aspects in ENT Surgery”. Conference series organize 3000+ Global Events inclusive of 2000+ Conferences, 500+ Workshops and 500+ symposiums on various topics of Science and Technology across the globe with support from 1,000 more scientific societies and Publishes 900+ Open access journals which contains over 50,000 eminent personalities, reputed Scientists as Editorial Board Members. Prestigious Award for Young Research’s at ENT Surgery 2020 - Discovering New Exploration in Surgery field. Surgery Conference Committee is intended to honour prestigious award for talented Young researchers, scientists, Young Investigators, Post-Graduate students, Post-doctoral fellows, Trainees, Junior faculty in recognition of their outstanding contribution towards the conference theme. The Young Scientist Awards make every effort in providing a strong professional development opportunity for early career academicians by meeting experts to exchange and share their experiences on all aspects of Surgery.
Hadi Nural
Surgery Conference Committee is glad to announce “5 th Global Meeting on Plastic, Aesthetic and Reconstructive Surgery” August 17 -18, 2020 in London, UK by focus on the theme: “Reviving new aspects in Plastic Surgery” Plastic Surgery Conf 2020 developments are maintaining their momentum. Surgery Conference program delves into strategic discussions Conference series organize 3000+ Global Events inclusive of 2000+ Conferences, 500+ Workshops and 500+ symposiums on various topics of Science and Technology across the globe with support from 1,000 more scientific societies and Publishes 900+ Open access journals which contains over 50,000 eminent personalities, reputed Scientists as Editorial Board Members.
Ergun Demirsoy
Surgery is a medical specialty in which different operative manual and instrumental techniques are applied on a patient to investigate or to treat some pathological conditions like disease or injury, to improve bodily function or appearance and repair unwanted ruptured areas. The act of surgical procedure is performed by a surgical team consisting of surgeons, surgeon’s assistant, anaesthetist, circulating nurse and surgical technologists. Surgeons and Physicians diagnose and treat illness and injuries in both humans and animals.
Suchi Spore
We deliver together industrial executives, neonatology pharma and health care sectors making the conference an excellent platform to network, share views and appreciation through interactive discussions. Worldwide, under-five mortality has considerably diminished over the closing decade from 90 deaths per 1,000 stay births in 1990, to forty-six per 1,000 in 2013. However, neonatal mortality has now not saved pace. Today, newborn deaths account for 44% of under-five deaths worldwide. Nearly a quarter of these deaths are triggered with the aid of unfavorable intra-partum events; a large percentage of these children die in their first 24 hours of life (Figure 1). Neonatal resuscitation can help ward off new child loss of life with the aid of supporting to set up adequate respiratory and circulation when newborns are unable to acquire these on their own. It is estimated that between 5%-10% of newborns at beginning require resuscitation.
Isabelle Gomez
I am pleased to mention that during the year 2019, all issues of volume 15 were published online well within the time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. Journal of Surgery [Jurnalul de chirurgie] during this year also brought out 4th Global Meeting on Plastic, Aesthetic and Reconstructive Surgery, which consisted of ~11 abstracts. The JCR Impact factor of JOS for the year 2018 was 1.91, while the current SJR index dropped to 0.256. The H-index of the journal, however, increased to 50 and JOS ranked first among all journals in the field of Surgical Sciences published in Indi a, 2nd in Asia and 48th in the world.
Danilov MA*, Baychorov AB and Leontev AV
Surgery is crucial in the treatment of Crohn's disease complications, particularly obstructive and septic. The risk of surgical complications in this patient group is particularly high due to transmural inflammation of the intestinal wall. If there is intestinal blockage in the compensatory stage, individuals with Crohn's disease are evaluated for routine surgical therapy.
Brain cancer deals with the different parts of the body. Brain tumor will come in brain and cancer will come in the other parts of the body. Brain tumor will develop due to the abnormal cells in the brain. When brain tumor arises there were so many problems to face for the human beings. In brain there are three types of functions are there in it called as cerebrum, cerebellum, and medulla. Brain has different structures in it. There are some types of tumors in brain are cancerous and some are non-cancerous tumors. Apart, from that the cancer will have the different type of nature and that was spread to brain from other parts of the body. It will affect the nervous system. It can cause a great harm to the body.
As past work, the diary of medical procedure has more productive part on the planet. Medical procedure implies primarily for supplanting something to other. Diary of Surgery will decides the degree that identified with some sort of productive thing, done by the innovation according to the convention of present field on the planet.
Juan Luis Giraldo Moreno* and Walter Emilio Osorio RamÃrez
We currently recognize uterine leiomyomas as a problem that affects thousands of women around the world. One in 5 women of reproductive age may suffer from uterine fibroids and up to 50% of women in their 50's have had fibroids at some point in their life time [1]. However uterine fibroids are benign fibromuscular tumors of the myometrium with low potential for malignancy, so many patients end up in a follow-up program that only offers to wait until their hormonal activity ends with menopause for symptoms related to with fibroids begin to disappear spontaneously.
Erdenebold Dashbazar1*, Baasanjav Nachin1, Batbold Baasanjav1, Puntsag Chimedtseyen2, Ganbaatar Mashbaljir2 and Altankhuyag Seseer2
About 20%-30% of patients with acute pancreatitis have a severe disease and mortality rate among inpatients were 15%. There are many causes of Acute Pancreatitis (AP), but most common cause of AP is an alcohol. In Mongolia, relatively young men suffer from alcohol-induced pancreatitis. Factors contributing to the development of necrosis in acute pancreatitis include alcohol abuse, prolonged alcohol use, delayed hospitalization, and delayed treatment. In our study, following clinical signs and laboratory findings are effective in distinguishing severe forms of acute necrotizing pancreatitis, early diagnosis, and assessment of prognosis. Laboratory tests parameters include of new recording system: increase in white blood cells, procalcitonin, serum amylase, serum LDH, serum lipase, C-reactive protein and a decrease in hematocrit, serum calcium.
M. Shadab Khan*, Asma Sarfaraz, Ramna Nadeem, Bushra Shirazi and Abdaal Waseem Khan
Introduction: Colorectal cancer the second most lethal malignancy widely considered a disease that affects people after the 4th decade of life but an interesting change in trend is observed and it was found that colorectal cancer rate has been increasing in young patients living under their 4th decade. These patients even present with more advanced diseases and generally have a poor overall prognosis compared to the older patients.
Materials and methods: Colorectal cancer patients presented in Sindh Institute of urology and transplantation’s Oncology center from January 2011 till December 2020 were reviewed retrospectively. For data analysis, all patients were divided into two groups, Group A young age population (age between 18-50 years) Group B old age population (age 51 years and onward).
Subgroup analysis of the study period (from January 2011 – December 2015 first period while from January 2016 – December 2020 second period) was performed to check the progressive change in the trend of stage and clinical characteristics of colorectal cancer in young and old patients. Details were reviewed from the patient’s files and all data was collected as per the Proforma requirement. Collected data was analyzed for results using SPSS version 23.0.
Results: Total of 612 patients with colorectal cancer presented between 2011 till 2020. Among these patients 243 (39.7%) presented between January 2011 till December 2015. Patients age 50 years and younger were 410 (66.8%).
Results showed a statistically significant association between patient age and tumor characteristics (histopathology and tumor differentiation). When data was analyzed over different study periods results showed that there is a statistically significant association between tumor differentiation and patient age. A change in the trend of clinical stage of the tumor with respect to patient age over this period of time was also noted.
Conclusion: The development and implementation of screening protocols and awareness programs will definitely have an impact to control disease incidence, patient prognosis, and survival outcome.
According to the European Cancer Information System (ECIS) female breast cancer is the most commonly diagnosed malignancy. More than 335,000 women in the European Union are considered to be diagnosed with breast cancer in 2020 which is 13.3% of all cancer diagnoses in both genders and 28.7% among the cancer diagnoses in women. The mortality rate is 7.3% being the third leading cause of cancer death for both genders after lung and colorectal cancer. Increased incidence rates are estimated in the Nordic countries. In the United States around 268,000 cases of invasive breast cancer and 48,100 cases of ductal carcinoma in situ were estimated to be diagnosed among US women in 2019 and 41,760 of them to die.
DOI: 10.37421/1584-9341.22.18.14
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DOI: 10.37421/ 1584-9341.2022.18.54
The definition of "sentinel" lymph nodes today has found wide application in clinical practice for complex examination and treatment of patients with cancer of the uterine body. Further research in this direction will help to optimize intraoperative staging of tumors. They will also allow avoiding extended surgeries and limiting themselves only to the removal of sentinel lymph nodes in the early stages of the disease. And vice versa, to expand the scope of the operation if lymphogenous metastases are detected outside the zone removed by standard lymph node dissection. The definition of SLN is sufficient to identify patients at high risk of recurrent EC and to plan adjuvant therapy.
DOI: 10.37421/ 1584-9341.2022.18.55
During the period from 2018 to 2020, hysteroresectoscopy was performed on 87 patients of late reproductive, pre- and postmenopausal age. The entire scope of examination, treatment and follow-up of patients before and after ablation was performed in the conditions of the NOVAMED Polyvalent Hospital. Indications for endometrial ablation are benign endometrial diseases, precancer and initial cancer of the uterine body (stage Ia) in patients of pre- and postmenopausal age with ineffectiveness, resistance, or contraindications to hormone therapy or radical surgical treatment due to pronounced extragenital. The results of the study allow us to recommend endometrial ablation as an alternative to classical methods of treatment (hormone therapy and extirpation of the uterus with appendages) in patients with atypical hyperplasia and initial endometrial cancer (Ia stage)
DOI: 10.37421/1584-9341.2022.18.56
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DOI: 10.37421/1584-9341.2022.18.58
Journal of Surgery received 288 citations as per Google Scholar report
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