Synthesis of 5-membered heterocyclic systems by the pummerer reaction

4^th European Chemistry Congress

May 11-13, 2017 Barcelona, Spain

Diego Gamba-Sanchez, Juan Rueda-Espinosa and Andres Gomez-Angel

University of Los Andes, Colombia

Posters & Accepted Abstracts: Chem Sci J

Abstract :

The Pummerer reaction has been studied for many years as a powerful methot to form C-Nu bonds, its aplications in total synthesis of natural products has been recently reviewed showing its grate potential. We recently publised a new method to obtain oxaxolines by Pummerer chemistry, and the goal of the current study is to extend the scope of this methodology to the synthesis of other heterocylcic systems. The results include approaches to pyrroles, ozaxoles, thiazoles and the application of the methodology to the total synthesis of siphonazole and muscoride A.

Biography :

Diego Gamba-Sanchez obtained his PhD in 2010 from the Ecole Polytechnique at Palaiseau.  After one year as a postdoctoral associate in the laboratory of Prof. Thorsten Bach, e moved back to Colombia ans started his independent carrier at the Universidad de los Andes in Bogotá. His research focused on new methodologies using Pummerer chemistry and the development of synthetic routes to natural products.
Email:da.gamba1361@uniandes.edu.co